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Clinical commissioning and use of the Novalis Tx linear accelerator for SRS and SBRT

The purpose of this study was to perform comprehensive measurements and testing of a Novalis Tx linear accelerator, and to develop technical guidelines for commissioning from the time of acceptance testing to the first clinical treatment. The Novalis Tx (NTX) linear accelerator is equipped with, amo...

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Autores principales: Kim, Jinkoo, Wen, Ning, Jin, Jian‐Yue, Walls, Nicole, Kim, Sangroh, Li, Haisen, Ren, Lei, Huang, Yimei, Doemer, Anthony, Faber, Kathleen, Kunkel, Tina, Balawi, Ahssan, Garbarino, Kimberly, Levin, Kenneth, Patel, Samir, Ajlouni, Munther, Miller, Brett, Nurushev, Teamor, Huntzinger, Calvin, Schulz, Raymond, Chetty, Indrin J., Movsas, Benjamin, Ryu, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716565/
https://www.ncbi.nlm.nih.gov/pubmed/22584170
http://dx.doi.org/10.1120/jacmp.v13i3.3729
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author Kim, Jinkoo
Wen, Ning
Jin, Jian‐Yue
Walls, Nicole
Kim, Sangroh
Li, Haisen
Ren, Lei
Huang, Yimei
Doemer, Anthony
Faber, Kathleen
Kunkel, Tina
Balawi, Ahssan
Garbarino, Kimberly
Levin, Kenneth
Patel, Samir
Ajlouni, Munther
Miller, Brett
Nurushev, Teamor
Huntzinger, Calvin
Schulz, Raymond
Chetty, Indrin J.
Movsas, Benjamin
Ryu, Samuel
author_facet Kim, Jinkoo
Wen, Ning
Jin, Jian‐Yue
Walls, Nicole
Kim, Sangroh
Li, Haisen
Ren, Lei
Huang, Yimei
Doemer, Anthony
Faber, Kathleen
Kunkel, Tina
Balawi, Ahssan
Garbarino, Kimberly
Levin, Kenneth
Patel, Samir
Ajlouni, Munther
Miller, Brett
Nurushev, Teamor
Huntzinger, Calvin
Schulz, Raymond
Chetty, Indrin J.
Movsas, Benjamin
Ryu, Samuel
author_sort Kim, Jinkoo
collection PubMed
description The purpose of this study was to perform comprehensive measurements and testing of a Novalis Tx linear accelerator, and to develop technical guidelines for commissioning from the time of acceptance testing to the first clinical treatment. The Novalis Tx (NTX) linear accelerator is equipped with, among other features, a high‐definition MLC (HD120 MLC) with 2.5 mm central leaves, a 6D robotic couch, an optical guidance positioning system, as well as X‐ray‐based image guidance tools to provide high accuracy radiation delivery for stereotactic radiosurgery and stereotactic body radiation therapy procedures. We have performed extensive tests for each of the components, and analyzed the clinical data collected in our clinic. We present technical guidelines in this report focusing on methods for: (1) efficient and accurate beam data collection for commissioning treatment planning systems, including small field output measurements conducted using a wide range of detectors; (2) commissioning tests for the HD120 MLC; (3) data collection for the baseline characteristics of the on‐board imager (OBI) and ExacTrac X‐ray (ETX) image guidance systems in conjunction with the 6D robotic couch; and (4) end‐to‐end testing of the entire clinical process. Established from our clinical experience thus far, recommendations are provided for accurate and efficient use of the OBI and ETX localization systems for intra‐ and extracranial treatment sites. Four results are presented. (1) Basic beam data measurements: Our measurements confirmed the necessity of using small detectors for small fields. Total scatter factors varied significantly (30% to approximately 62%) for small field measurements among detectors. Unshielded stereotactic field diode (SFD) overestimated dose by [Formula: see text] for large field sizes. Ion chambers with active diameters of 6 mm suffered from significant volume averaging. The sharpest profile penumbra was observed for the SFD because of its small active diameter (0.6 mm). (2) MLC commissioning: Winston Lutz test, light/radiation field congruence, and Picket Fence tests were performed and were within criteria established by the relevant task group reports. The measured mean MLC transmission and dynamic leaf gap of 6 MV SRS beam were 1.17% and 0.36 mm, respectively. (3) Baseline characteristics of OBI and ETX: The isocenter localization errors in the left/right, posterior/anterior, and superior/inferior directions were, respectively, [Formula: see text] , [Formula: see text] , and [Formula: see text] for ETX, and [Formula: see text] , [Formula: see text] , and [Formula: see text] for OBI cone‐beam computed tomography. The registration angular discrepancy was [Formula: see text] , and the maximum robotic couch error was 0.2°. (4) End‐to‐end tests: The measured isocenter dose differences from the planned values were 0.8% and 0.4%, measured respectively by an ion chamber and film. The gamma pass rate, measured by EBT2 film, was 95% (3% DD and 1 mm DTA). Through a systematic series of quantitative commissioning experiments and end‐to‐end tests and our initial clinical experience, described in this report, we demonstrate that the NTX is a robust system, with the image guidance and MLC requirements to treat a wide variety of sites — in particular for highly accurate delivery of SRS and SBRT‐based treatments. PACS numbers: 87.55.Qr, 87.53.Ly, 87.59.‐e
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spelling pubmed-57165652018-04-02 Clinical commissioning and use of the Novalis Tx linear accelerator for SRS and SBRT Kim, Jinkoo Wen, Ning Jin, Jian‐Yue Walls, Nicole Kim, Sangroh Li, Haisen Ren, Lei Huang, Yimei Doemer, Anthony Faber, Kathleen Kunkel, Tina Balawi, Ahssan Garbarino, Kimberly Levin, Kenneth Patel, Samir Ajlouni, Munther Miller, Brett Nurushev, Teamor Huntzinger, Calvin Schulz, Raymond Chetty, Indrin J. Movsas, Benjamin Ryu, Samuel J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study was to perform comprehensive measurements and testing of a Novalis Tx linear accelerator, and to develop technical guidelines for commissioning from the time of acceptance testing to the first clinical treatment. The Novalis Tx (NTX) linear accelerator is equipped with, among other features, a high‐definition MLC (HD120 MLC) with 2.5 mm central leaves, a 6D robotic couch, an optical guidance positioning system, as well as X‐ray‐based image guidance tools to provide high accuracy radiation delivery for stereotactic radiosurgery and stereotactic body radiation therapy procedures. We have performed extensive tests for each of the components, and analyzed the clinical data collected in our clinic. We present technical guidelines in this report focusing on methods for: (1) efficient and accurate beam data collection for commissioning treatment planning systems, including small field output measurements conducted using a wide range of detectors; (2) commissioning tests for the HD120 MLC; (3) data collection for the baseline characteristics of the on‐board imager (OBI) and ExacTrac X‐ray (ETX) image guidance systems in conjunction with the 6D robotic couch; and (4) end‐to‐end testing of the entire clinical process. Established from our clinical experience thus far, recommendations are provided for accurate and efficient use of the OBI and ETX localization systems for intra‐ and extracranial treatment sites. Four results are presented. (1) Basic beam data measurements: Our measurements confirmed the necessity of using small detectors for small fields. Total scatter factors varied significantly (30% to approximately 62%) for small field measurements among detectors. Unshielded stereotactic field diode (SFD) overestimated dose by [Formula: see text] for large field sizes. Ion chambers with active diameters of 6 mm suffered from significant volume averaging. The sharpest profile penumbra was observed for the SFD because of its small active diameter (0.6 mm). (2) MLC commissioning: Winston Lutz test, light/radiation field congruence, and Picket Fence tests were performed and were within criteria established by the relevant task group reports. The measured mean MLC transmission and dynamic leaf gap of 6 MV SRS beam were 1.17% and 0.36 mm, respectively. (3) Baseline characteristics of OBI and ETX: The isocenter localization errors in the left/right, posterior/anterior, and superior/inferior directions were, respectively, [Formula: see text] , [Formula: see text] , and [Formula: see text] for ETX, and [Formula: see text] , [Formula: see text] , and [Formula: see text] for OBI cone‐beam computed tomography. The registration angular discrepancy was [Formula: see text] , and the maximum robotic couch error was 0.2°. (4) End‐to‐end tests: The measured isocenter dose differences from the planned values were 0.8% and 0.4%, measured respectively by an ion chamber and film. The gamma pass rate, measured by EBT2 film, was 95% (3% DD and 1 mm DTA). Through a systematic series of quantitative commissioning experiments and end‐to‐end tests and our initial clinical experience, described in this report, we demonstrate that the NTX is a robust system, with the image guidance and MLC requirements to treat a wide variety of sites — in particular for highly accurate delivery of SRS and SBRT‐based treatments. PACS numbers: 87.55.Qr, 87.53.Ly, 87.59.‐e John Wiley and Sons Inc. 2012-05-10 /pmc/articles/PMC5716565/ /pubmed/22584170 http://dx.doi.org/10.1120/jacmp.v13i3.3729 Text en © 2012 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Kim, Jinkoo
Wen, Ning
Jin, Jian‐Yue
Walls, Nicole
Kim, Sangroh
Li, Haisen
Ren, Lei
Huang, Yimei
Doemer, Anthony
Faber, Kathleen
Kunkel, Tina
Balawi, Ahssan
Garbarino, Kimberly
Levin, Kenneth
Patel, Samir
Ajlouni, Munther
Miller, Brett
Nurushev, Teamor
Huntzinger, Calvin
Schulz, Raymond
Chetty, Indrin J.
Movsas, Benjamin
Ryu, Samuel
Clinical commissioning and use of the Novalis Tx linear accelerator for SRS and SBRT
title Clinical commissioning and use of the Novalis Tx linear accelerator for SRS and SBRT
title_full Clinical commissioning and use of the Novalis Tx linear accelerator for SRS and SBRT
title_fullStr Clinical commissioning and use of the Novalis Tx linear accelerator for SRS and SBRT
title_full_unstemmed Clinical commissioning and use of the Novalis Tx linear accelerator for SRS and SBRT
title_short Clinical commissioning and use of the Novalis Tx linear accelerator for SRS and SBRT
title_sort clinical commissioning and use of the novalis tx linear accelerator for srs and sbrt
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716565/
https://www.ncbi.nlm.nih.gov/pubmed/22584170
http://dx.doi.org/10.1120/jacmp.v13i3.3729
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