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Conformational dynamics in TRPV1 channels reported by an encoded coumarin amino acid
TRPV1 channels support the detection of noxious and nociceptive input. Currently available functional and structural data suggest that TRPV1 channels have two gates within their permeation pathway: one formed by a ′bundle-crossing′ at the intracellular entrance and a second constriction at the selec...
Autores principales: | Steinberg, Ximena, Kasimova, Marina A, Cabezas-Bratesco, Deny, Galpin, Jason D, Ladron-de-Guevara, Ernesto, Villa, Federica, Carnevale, Vincenzo, Islas, Leon, Ahern, Christopher A, Brauchi, Sebastian E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716661/ https://www.ncbi.nlm.nih.gov/pubmed/29206105 http://dx.doi.org/10.7554/eLife.28626 |
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