Pro-invasive properties of Snail1 are regulated by sumoylation in response to TGFβ stimulation in cancer

Transforming growth factor β (TGFβ) is a key regulator of epithelial-to-mesenchymal transition (EMT) during embryogenesis and in tumors. The effect of TGFβ, on ΕΜΤ, is conveyed by induction of the pro-invasive transcription factor Snail1. In this study, we report that TGFβ stimulates Snail1 sumoylat...

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Detalles Bibliográficos
Autores principales: Gudey, Shyam Kumar, Sundar, Reshma, Heldin, Carl-Henrik, Bergh, Anders, Landström, Marene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716685/
https://www.ncbi.nlm.nih.gov/pubmed/29228645
http://dx.doi.org/10.18632/oncotarget.20097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716685/
https://www.ncbi.nlm.nih.gov/pubmed/29228645
http://dx.doi.org/10.18632/oncotarget.20097

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