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Lack of chemopreventive effects of P2X7R inhibitors against pancreatic cancer

Pancreatic cancer (PC) is an almost uniformly lethal disease with inflammation playing an important role in its progression. Sustained stimulation of purinergic receptor P2X7 drives induction of NLRP inflammasome activation. To understand the role of P2X7 receptor and inflammasome, we performed tran...

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Detalles Bibliográficos
Autores principales:	Mohammed, Altaf, Janakiram, Naveena B., Madka, Venkateshwar, Pathuri, Gopal, Li, Qian, Ritchie, Rebekah, Biddick, Laura, Kutche, Hannah, Zhang, Yuting, Singh, Anil, Gali, Hariprasad, Lightfoot, Stan, Steele, Vernon E., Suen, Chen S., Rao, Chinthalapally V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716694/ https://www.ncbi.nlm.nih.gov/pubmed/29228654 http://dx.doi.org/10.18632/oncotarget.22085

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