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Increased PDGFR-beta and VEGFR-2 protein levels are associated with resistance to platinum-based chemotherapy and adverse outcome of ovarian cancer patients

Despite frequent initial response rates of epithelial ovarian cancer to platinum-based chemotherapy the majority of patients develop drug resistance. Our aim was to evaluate differential expression of signaling-pathway proteins in platinum-sensitive versus platinum-resistant primary epithelial ovari...

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Detalles Bibliográficos
Autores principales: Avril, Stefanie, Dincer, Yasemin, Malinowsky, Katharina, Wolff, Claudia, Gündisch, Sibylle, Hapfelmeier, Alexander, Boxberg, Melanie, Bronger, Holger, Becker, Karl-Friedrich, Schmalfeldt, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716696/
https://www.ncbi.nlm.nih.gov/pubmed/29228656
http://dx.doi.org/10.18632/oncotarget.18415