Targeting PLK1 as a novel chemopreventive approach to eradicate preneoplastic mucosal changes in the head and neck

Head and neck squamous cell carcinomas (HNSCC) and local relapses thereof develop in preneoplastic fields in the mucosal linings of the upper aerodigestive tract. These fields are characterized by tumor-associated genetic changes, are frequently dysplastic and occasionally macroscopically visible. C...

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Detalles Bibliográficos
Autores principales: de Boer, D. Vicky, Martens-de Kemp, Sanne R., Buijze, Marijke, Stigter-van Walsum, Marijke, Bloemena, Elisabeth, Dietrich, Ralf, Leemans, C. René, van Beusechem, Victor W., Braakhuis, Boudewijn J.M., Brakenhoff, Ruud H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716703/
https://www.ncbi.nlm.nih.gov/pubmed/29228663
http://dx.doi.org/10.18632/oncotarget.17880

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716703/
https://www.ncbi.nlm.nih.gov/pubmed/29228663
http://dx.doi.org/10.18632/oncotarget.17880

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