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PTEN regulates spindle assembly checkpoint timing through MAD1 in interphase

The spindle assembly checkpoint (SAC) restrains anaphase progression to ensure all chromosomes attach properly to the spindle. Although SAC timing has been extensively investigated in mitosis, its mechanism of regulation in interphase is unclear. We report that PTEN functions as a crucial activator...

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Detalles Bibliográficos
Autores principales:	Liu, Yu, Du, Xiao, Zhang, Shuting, Liu, Yang, Zhang, Qiaoling, Yin, Qi, McNutt, Michael A., Yin, Yuxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716712/ https://www.ncbi.nlm.nih.gov/pubmed/29228672 http://dx.doi.org/10.18632/oncotarget.20532

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