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Lenalidomide overcomes the immunosuppression of regulatory CD8(+)CD28(−) T-cells
Although lenalidomide and pomalidomide are well-established treatment options in patients with multiple myeloma, their immune-modulating effects are not fully understood. While CD8(+)CD28(−) regulatory T-cells in patients with hematologic disorders display a known immune-escape mechanism, we show th...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716723/ https://www.ncbi.nlm.nih.gov/pubmed/29228683 http://dx.doi.org/10.18632/oncotarget.21516 |