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A systematic assessment of chemical, genetic, and epigenetic factors influencing the activity of anticancer drug KP1019 (FFC14A)
KP1019 ([trans-RuCl(4)(1H-indazole)(2)]; FFC14A) is one of the promising ruthenium-based anticancer drugs undergoing clinical trials. Despite the pre-clinical and clinical success of KP1019, the mode of action and various factors capable of modulating its effects are largely unknown. Here, we used t...
Autores principales: | Golla, Upendarrao, Swagatika, Swati, Chauhan, Sakshi, Tomar, Raghuvir Singh |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716741/ https://www.ncbi.nlm.nih.gov/pubmed/29228701 http://dx.doi.org/10.18632/oncotarget.21416 |
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