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Hoxa9 and Hoxa10 induce CML myeloid blast crisis development through activation of Myb expression

Mechanisms underlying the progression of Chronic Myeloid Leukemia (CML) from chronic phase to myeloid blast crisis are poorly understood. Our previous studies have suggested that overexpression of SETBP1 can drive this progression by conferring unlimited self-renewal capability to granulocyte macrop...

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Detalles Bibliográficos
Autores principales: Negi, Vijay, Vishwakarma, Bandana A., Chu, Su, Oakley, Kevin, Han, Yufen, Bhatia, Ravi, Du, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716772/
https://www.ncbi.nlm.nih.gov/pubmed/29228732
http://dx.doi.org/10.18632/oncotarget.22008