Targeting tumor-associated carbohydrate antigens: a phase I study of a carbohydrate mimetic-peptide vaccine in stage IV breast cancer subjects

Tumor-associated carbohydrate antigens (TACAs) support cell survival that could be interrupted by anti-TACA antibodies. Among TACAs that mediate cell survival signals are the neolactoseries antigen Lewis Y (LeY) and the ganglioside GD2. To induce sustained immunity against both LeY and GD2, we devel...

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Detalles Bibliográficos
Autores principales: Hutchins, Laura F., Makhoul, Issam, Emanuel, Peter D., Pennisi, Angela, Siegel, Eric R., Jousheghany, Fariba, Guo, Xueyan, Pashov, Anastas D., Monzavi-Karbassi, Behjatolah, Kieber-Emmons, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Clinical Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716801/
https://www.ncbi.nlm.nih.gov/pubmed/29228761
http://dx.doi.org/10.18632/oncotarget.21959

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