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Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade
Phenotypic switch of vascular smooth muscle cells (VSMCs) is characterized by increased expressions of VSMC synthetic markers and decreased levels of VSMC contractile markers, which is an important step for VSMC proliferation and migration during the development and progression of cardiovascular dis...
Autores principales: | Lu, Qing-Bo, Wan, Ming-Yu, Wang, Pei-Yao, Zhang, Chen-Xing, Xu, Dong-Yan, Liao, Xiang, Sun, Hai-Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716955/ https://www.ncbi.nlm.nih.gov/pubmed/29175753 http://dx.doi.org/10.1016/j.redox.2017.11.012 |
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