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Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade

Phenotypic switch of vascular smooth muscle cells (VSMCs) is characterized by increased expressions of VSMC synthetic markers and decreased levels of VSMC contractile markers, which is an important step for VSMC proliferation and migration during the development and progression of cardiovascular dis...

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Detalles Bibliográficos
Autores principales: Lu, Qing-Bo, Wan, Ming-Yu, Wang, Pei-Yao, Zhang, Chen-Xing, Xu, Dong-Yan, Liao, Xiang, Sun, Hai-Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716955/
https://www.ncbi.nlm.nih.gov/pubmed/29175753
http://dx.doi.org/10.1016/j.redox.2017.11.012

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