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Novel Mechanism of the Pericyte-Myofibroblast Transition in Renal Interstitial Fibrosis: Core Fucosylation Regulation
Pericytes have been identified as a major source of myofibroblasts in renal interstitial fibrosis (RIF). The overactivation of several signaling pathways, mainly the TGF-β and PDGF pathways, initiates the pericyte-myofibroblast transition during RIF. Key receptors in these two pathways have been sho...
Autores principales: | Wang, Nan, Deng, Yiyao, Liu, Anqi, Shen, Nan, Wang, Weidong, Du, Xiangning, Tang, Qingzhu, Li, Shuangxin, Odeh, Zach, Wu, Taihua, Lin, Hongli |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717002/ https://www.ncbi.nlm.nih.gov/pubmed/29209018 http://dx.doi.org/10.1038/s41598-017-17193-5 |
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