Alterations in B Cell Compartment Correlate with Poor Neutralization Response and Disease Progression in HIV-1 Infected Children

Several B cell defects are reported in HIV-1 infected individuals including variation in B cell subsets, polyclonal B cell activation and exhaustion, with broadly neutralizing antibodies elicited in less than 10–20% of the infected population. HIV-1 disease progression is faster in children than adu...

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Detalles Bibliográficos
Autores principales: Aggarwal, Heena, Khan, Lubina, Chaudhary, Omkar, Kumar, Sanjeev, Makhdoomi, Muzamil Ashraf, Singh, Ravinder, Sharma, Kanika, Mishra, Nitesh, Lodha, Rakesh, Srinivas, Maddur, Das, Bimal Kumar, Kabra, Sushil Kumar, Luthra, Kalpana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717014/
https://www.ncbi.nlm.nih.gov/pubmed/29250072
http://dx.doi.org/10.3389/fimmu.2017.01697

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