Polη O-GlcNAcylation governs genome integrity during translesion DNA synthesis

DNA polymerase η (Polη) facilitates translesion DNA synthesis (TLS) across ultraviolet (UV) irradiation- and cisplatin-induced DNA lesions implicated in skin carcinogenesis and chemoresistant phenotype formation, respectively. However, whether post-translational modifications of Polη are involved in...

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Detalles Bibliográficos
Autores principales: Ma, Xiaolu, Liu, Hongmei, Li, Jing, Wang, Yihao, Ding, Yue-He, Shen, Hongyan, Yang, Yeran, Sun, Chenyi, Huang, Min, Tu, Yingfeng, Liu, Yang, Zhao, Yongliang, Dong, Meng-Qiu, Xu, Ping, Tang, Tie-Shan, Guo, Caixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717138/
https://www.ncbi.nlm.nih.gov/pubmed/29208956
http://dx.doi.org/10.1038/s41467-017-02164-1

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