Randomized, Placebo-Controlled, Double-Blind Phase 2 Trial Comparing the Reactogenicity and Immunogenicity of a Single Standard Dose to Those of a High Dose of CVD 103-HgR Live Attenuated Oral Cholera Vaccine, with Shanchol Inactivated Oral Vaccine as an Open-Label Immunologic Comparator

Reactive immunization with a single-dose cholera vaccine that could rapidly (within days) protect immunologically naive individuals during virgin soil epidemics, when cholera reaches immunologically naive populations that have not experienced cholera for decades, would facilitate cholera control. On...

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Detalles Bibliográficos
Autores principales: Sow, Samba O., Tapia, Milagritos D., Chen, Wilbur H., Haidara, Fadima C., Kotloff, Karen L., Pasetti, Marcela F., Blackwelder, William C., Traoré, Awa, Tamboura, Boubou, Doumbia, Moussa, Diallo, Fatoumata, Coulibaly, Flanon, Onwuchekwa, Uma, Kodio, Mamoudou, Tennant, Sharon M., Reymann, Mardi, Lam, Diana F., Gurwith, Marc, Lock, Michael, Yonker, Thomas, Smith, Jonathan, Simon, Jakub K., Levine, Myron M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Vaccines
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717191/
https://www.ncbi.nlm.nih.gov/pubmed/29021299
http://dx.doi.org/10.1128/CVI.00265-17

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