The NDE1 genomic locus can affect treatment of psychiatric illness through gene expression changes related to microRNA-484

Genetic studies of familial schizophrenia in Finland have observed significant associations with a group of biologically related genes, DISC1, NDE1, NDEL1, PDE4B and PDE4D, the ‘DISC1 network’. Here, we use gene expression and psychoactive medication use data to study their biological consequences a...

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Detalles Bibliográficos
Autores principales: Bradshaw, Nicholas J., Ukkola-Vuoti, Liisa, Pankakoski, Maiju, Zheutlin, Amanda B., Ortega-Alonso, Alfredo, Torniainen-Holm, Minna, Sinha, Vishal, Therman, Sebastian, Paunio, Tiina, Suvisaari, Jaana, Lönnqvist, Jouko, Cannon, Tyrone D., Haukka, Jari, Hennah, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717342/
https://www.ncbi.nlm.nih.gov/pubmed/29142105
http://dx.doi.org/10.1098/rsob.170153

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