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Visualizing the complex functions and mechanisms of the anaphase promoting complex/cyclosome (APC/C)

The anaphase promoting complex or cyclosome (APC/C) is a large multi-subunit E3 ubiquitin ligase that orchestrates cell cycle progression by mediating the degradation of important cell cycle regulators. During the two decades since its discovery, much has been learnt concerning its role in recognizi...

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Detalles Bibliográficos
Autores principales: Alfieri, Claudio, Zhang, Suyang, Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717348/
https://www.ncbi.nlm.nih.gov/pubmed/29167309
http://dx.doi.org/10.1098/rsob.170204