Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis

Hyperactivation of Wnt/β-catenin signaling is one of the major causes of human colorectal cancer (CRC). A hallmark of Wnt signaling is the nuclear accumulation of β-catenin. Although β-catenin nuclear import and export have been widely investigated, the underlying mechanism of β-catenin's nucle...

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Detalles Bibliográficos
Autores principales: Lu, Yi, Xie, Shanshan, Zhang, Wen, Zhang, Cheng, Gao, Cheng, Sun, Qiang, Cai, Yuqi, Xu, Zhangqi, Xiao, Min, Xu, Yanjun, Huang, Xiao, Wu, Ximei, Liu, Wei, Wang, Fudi, Kang, Yibin, Zhou, Tianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717399/
https://www.ncbi.nlm.nih.gov/pubmed/28829046
http://dx.doi.org/10.1038/cr.2017.107

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