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When and how should multiple imputation be used for handling missing data in randomised clinical trials – a practical guide with flowcharts
BACKGROUND: Missing data may seriously compromise inferences from randomised clinical trials, especially if missing data are not handled appropriately. The potential bias due to missing data depends on the mechanism causing the data to be missing, and the analytical methods applied to amend the miss...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717805/ https://www.ncbi.nlm.nih.gov/pubmed/29207961 http://dx.doi.org/10.1186/s12874-017-0442-1 |