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Role of endoplasmic reticulum stress in the protective effects of PPARβ/δ activation on endothelial dysfunction induced by plasma from patients with lupus

BACKGROUND: We tested whether GW0742, a peroxisome proliferator-activated receptor beta/delta (PPARβ/δ) agonist, improves endothelial dysfunction induced by plasma from patients with systemic lupus erythematosus (SLE) involving the inhibition of endoplasmic reticulum (ER) stress. METHODS: A total of...

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Detalles Bibliográficos
Autores principales:	Toral, Marta, Jiménez, Rosario, Romero, Miguel, Robles-Vera, Iñaki, Sánchez, Manuel, Salaices, Mercedes, Sabio, José Mario, Duarte, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717848/ https://www.ncbi.nlm.nih.gov/pubmed/29208022 http://dx.doi.org/10.1186/s13075-017-1478-7

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