Cargando…

Balloon Angioplasty as a Modality to Treat Children with Pulmonary Stenosis Secondary to Complex Congenital Heart Diseases

BACKGROUND: Pulmonary stenosis is common in children with complex congenital heart diseases. Proper management of this problem, especially postoperatively, is still controversial. This study was designed to assess the rate and determinants of success or failure of balloon angioplasty for such lesion...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Yan, Jin, Mei, Wang, Xiao-Fang, Guo, Bao-Jing, Ding, Wen-Hong, Wang, Zhi-Yuan, Zhang, Ya-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717857/
https://www.ncbi.nlm.nih.gov/pubmed/28952468
http://dx.doi.org/10.4103/0366-6999.215715
_version_ 1783284227012296704
author Gu, Yan
Jin, Mei
Wang, Xiao-Fang
Guo, Bao-Jing
Ding, Wen-Hong
Wang, Zhi-Yuan
Zhang, Ya-Hui
author_facet Gu, Yan
Jin, Mei
Wang, Xiao-Fang
Guo, Bao-Jing
Ding, Wen-Hong
Wang, Zhi-Yuan
Zhang, Ya-Hui
author_sort Gu, Yan
collection PubMed
description BACKGROUND: Pulmonary stenosis is common in children with complex congenital heart diseases. Proper management of this problem, especially postoperatively, is still controversial. This study was designed to assess the rate and determinants of success or failure of balloon angioplasty for such lesions. METHODS: Clinical and hemodynamic data from 40 pediatric patients (24 boys and 16 girls) with complex congenital heart diseases who underwent balloon angioplasty were reviewed retrospectively from January 2012 to December 2016. Patients were divided into four groups according to the site of stenosis, which included pulmonary valve stenosis (PVS), valved conduit stenosis, pulmonary artery stenosis (PAS), and supravalvular pulmonary stenosis (SVPS). Success rates were calculated according to defined criteria for initial success and favorable clinical impacts, and comparison between the successful subgroup and the unsuccessful subgroups was analyzed. RESULTS: Grouped by the site of stenosis, initial success rates varied from 40.0% to 52.4% with the greatest success being seen in the PVS group, followed by the PAS group and SVPS group. In the PVS group and the PAS group, there was no statistical difference among age at dilation, postoperative interval, balloon/stenosis ratio, or pressure gradient predilation between the successful and the unsuccessful subgroups. Favorable clinical impacts included success rates of balloon angioplasty in the SVPS group, which was best (100%), followed by the PVS group (90.9%) and the PAS group (85.7%). There were a total of two transient complications (5.0%). CONCLUSIONS: Balloon angioplasty was proven to be a safe and useful modality in children with complex congenital heart diseases and postoperative pulmonary stenosis, which should be the initial therapeutic modality in selected patients.
format Online
Article
Text
id pubmed-5717857
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-57178572017-12-20 Balloon Angioplasty as a Modality to Treat Children with Pulmonary Stenosis Secondary to Complex Congenital Heart Diseases Gu, Yan Jin, Mei Wang, Xiao-Fang Guo, Bao-Jing Ding, Wen-Hong Wang, Zhi-Yuan Zhang, Ya-Hui Chin Med J (Engl) Original Article BACKGROUND: Pulmonary stenosis is common in children with complex congenital heart diseases. Proper management of this problem, especially postoperatively, is still controversial. This study was designed to assess the rate and determinants of success or failure of balloon angioplasty for such lesions. METHODS: Clinical and hemodynamic data from 40 pediatric patients (24 boys and 16 girls) with complex congenital heart diseases who underwent balloon angioplasty were reviewed retrospectively from January 2012 to December 2016. Patients were divided into four groups according to the site of stenosis, which included pulmonary valve stenosis (PVS), valved conduit stenosis, pulmonary artery stenosis (PAS), and supravalvular pulmonary stenosis (SVPS). Success rates were calculated according to defined criteria for initial success and favorable clinical impacts, and comparison between the successful subgroup and the unsuccessful subgroups was analyzed. RESULTS: Grouped by the site of stenosis, initial success rates varied from 40.0% to 52.4% with the greatest success being seen in the PVS group, followed by the PAS group and SVPS group. In the PVS group and the PAS group, there was no statistical difference among age at dilation, postoperative interval, balloon/stenosis ratio, or pressure gradient predilation between the successful and the unsuccessful subgroups. Favorable clinical impacts included success rates of balloon angioplasty in the SVPS group, which was best (100%), followed by the PVS group (90.9%) and the PAS group (85.7%). There were a total of two transient complications (5.0%). CONCLUSIONS: Balloon angioplasty was proven to be a safe and useful modality in children with complex congenital heart diseases and postoperative pulmonary stenosis, which should be the initial therapeutic modality in selected patients. Medknow Publications & Media Pvt Ltd 2017-12-05 /pmc/articles/PMC5717857/ /pubmed/28952468 http://dx.doi.org/10.4103/0366-6999.215715 Text en Copyright: © 2017 Chinese Medical Journal http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Original Article
Gu, Yan
Jin, Mei
Wang, Xiao-Fang
Guo, Bao-Jing
Ding, Wen-Hong
Wang, Zhi-Yuan
Zhang, Ya-Hui
Balloon Angioplasty as a Modality to Treat Children with Pulmonary Stenosis Secondary to Complex Congenital Heart Diseases
title Balloon Angioplasty as a Modality to Treat Children with Pulmonary Stenosis Secondary to Complex Congenital Heart Diseases
title_full Balloon Angioplasty as a Modality to Treat Children with Pulmonary Stenosis Secondary to Complex Congenital Heart Diseases
title_fullStr Balloon Angioplasty as a Modality to Treat Children with Pulmonary Stenosis Secondary to Complex Congenital Heart Diseases
title_full_unstemmed Balloon Angioplasty as a Modality to Treat Children with Pulmonary Stenosis Secondary to Complex Congenital Heart Diseases
title_short Balloon Angioplasty as a Modality to Treat Children with Pulmonary Stenosis Secondary to Complex Congenital Heart Diseases
title_sort balloon angioplasty as a modality to treat children with pulmonary stenosis secondary to complex congenital heart diseases
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717857/
https://www.ncbi.nlm.nih.gov/pubmed/28952468
http://dx.doi.org/10.4103/0366-6999.215715
work_keys_str_mv AT guyan balloonangioplastyasamodalitytotreatchildrenwithpulmonarystenosissecondarytocomplexcongenitalheartdiseases
AT jinmei balloonangioplastyasamodalitytotreatchildrenwithpulmonarystenosissecondarytocomplexcongenitalheartdiseases
AT wangxiaofang balloonangioplastyasamodalitytotreatchildrenwithpulmonarystenosissecondarytocomplexcongenitalheartdiseases
AT guobaojing balloonangioplastyasamodalitytotreatchildrenwithpulmonarystenosissecondarytocomplexcongenitalheartdiseases
AT dingwenhong balloonangioplastyasamodalitytotreatchildrenwithpulmonarystenosissecondarytocomplexcongenitalheartdiseases
AT wangzhiyuan balloonangioplastyasamodalitytotreatchildrenwithpulmonarystenosissecondarytocomplexcongenitalheartdiseases
AT zhangyahui balloonangioplastyasamodalitytotreatchildrenwithpulmonarystenosissecondarytocomplexcongenitalheartdiseases