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Non-seminomatous germ cell tumor with bone metastasis only at diagnosis: A rare clinical presentation

Bone metastasis of non-seminomatous germ cell tumors (NSGCT) of the testes is a rare event and even more uncommon at initial presentation. Generally, bone lesions are discovered in the presence of concurrent retroperitoneal lymph node or visceral disease. However, in this case, a 37 years old male c...

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Autores principales: Biebighauser, K.C., Gao, Jianjun, Rao, Priya, Landon, Gene, Pagliaro, Lance, Dinney, Colin P.N., Karam, Jose, Navai, Neema
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Second Military Medical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717982/
https://www.ncbi.nlm.nih.gov/pubmed/29264217
http://dx.doi.org/10.1016/j.ajur.2016.08.004
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author Biebighauser, K.C.
Gao, Jianjun
Rao, Priya
Landon, Gene
Pagliaro, Lance
Dinney, Colin P.N.
Karam, Jose
Navai, Neema
author_facet Biebighauser, K.C.
Gao, Jianjun
Rao, Priya
Landon, Gene
Pagliaro, Lance
Dinney, Colin P.N.
Karam, Jose
Navai, Neema
author_sort Biebighauser, K.C.
collection PubMed
description Bone metastasis of non-seminomatous germ cell tumors (NSGCT) of the testes is a rare event and even more uncommon at initial presentation. Generally, bone lesions are discovered in the presence of concurrent retroperitoneal lymph node or visceral disease. However, in this case, a 37 years old male complaining of a growing testicular mass was found to have isolated bone metastasis with associated caudaequina syndrome without apparent abnormal findings on initial computed tomography (CT) scans. Continued neurologic symptoms prompted further evaluation with magnetic resonance imaging (MRI), which demonstrated multiple sites of bone metastasis without evidence of retroperitoneal lymph node or visceral organ involvement. This case represents a rare clinical presentation and disease manifestation of NSGCT.
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spelling pubmed-57179822017-12-20 Non-seminomatous germ cell tumor with bone metastasis only at diagnosis: A rare clinical presentation Biebighauser, K.C. Gao, Jianjun Rao, Priya Landon, Gene Pagliaro, Lance Dinney, Colin P.N. Karam, Jose Navai, Neema Asian J Urol Case Report Bone metastasis of non-seminomatous germ cell tumors (NSGCT) of the testes is a rare event and even more uncommon at initial presentation. Generally, bone lesions are discovered in the presence of concurrent retroperitoneal lymph node or visceral disease. However, in this case, a 37 years old male complaining of a growing testicular mass was found to have isolated bone metastasis with associated caudaequina syndrome without apparent abnormal findings on initial computed tomography (CT) scans. Continued neurologic symptoms prompted further evaluation with magnetic resonance imaging (MRI), which demonstrated multiple sites of bone metastasis without evidence of retroperitoneal lymph node or visceral organ involvement. This case represents a rare clinical presentation and disease manifestation of NSGCT. Second Military Medical University 2017-04 2016-08-26 /pmc/articles/PMC5717982/ /pubmed/29264217 http://dx.doi.org/10.1016/j.ajur.2016.08.004 Text en © 2017 Editorial Office of Asian Journal of Urology. Production and hosting by Elsevier B.V. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Biebighauser, K.C.
Gao, Jianjun
Rao, Priya
Landon, Gene
Pagliaro, Lance
Dinney, Colin P.N.
Karam, Jose
Navai, Neema
Non-seminomatous germ cell tumor with bone metastasis only at diagnosis: A rare clinical presentation
title Non-seminomatous germ cell tumor with bone metastasis only at diagnosis: A rare clinical presentation
title_full Non-seminomatous germ cell tumor with bone metastasis only at diagnosis: A rare clinical presentation
title_fullStr Non-seminomatous germ cell tumor with bone metastasis only at diagnosis: A rare clinical presentation
title_full_unstemmed Non-seminomatous germ cell tumor with bone metastasis only at diagnosis: A rare clinical presentation
title_short Non-seminomatous germ cell tumor with bone metastasis only at diagnosis: A rare clinical presentation
title_sort non-seminomatous germ cell tumor with bone metastasis only at diagnosis: a rare clinical presentation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717982/
https://www.ncbi.nlm.nih.gov/pubmed/29264217
http://dx.doi.org/10.1016/j.ajur.2016.08.004
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