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Treatment of Major Depressive Disorder with Iyengar Yoga and Coherent Breathing: A Randomized Controlled Dosing Study

Objectives: The aims of this study were to assess the effects of an intervention of Iyengar yoga and coherent breathing at five breaths per minute on depressive symptoms and to determine optimal intervention yoga dosing for future studies in individuals with major depressive disorder (MDD). Methods:...

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Autores principales: Streeter, Chris C., Gerbarg, Patricia L., Whitfield, Theodore H., Owen, Liz, Johnston, Jennifer, Silveri, Marisa M., Gensler, Marysia, Faulkner, Carol L., Mann, Cathy, Wixted, Mary, Hernon, Anne Marie, Nyer, Maren B., Brown, E. Richard P., Jensen, John E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717996/
https://www.ncbi.nlm.nih.gov/pubmed/29225455
http://dx.doi.org/10.1089/act.2017.29134.ccs
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author Streeter, Chris C.
Gerbarg, Patricia L.
Whitfield, Theodore H.
Owen, Liz
Johnston, Jennifer
Silveri, Marisa M.
Gensler, Marysia
Faulkner, Carol L.
Mann, Cathy
Wixted, Mary
Hernon, Anne Marie
Nyer, Maren B.
Brown, E. Richard P.
Jensen, John E.
author_facet Streeter, Chris C.
Gerbarg, Patricia L.
Whitfield, Theodore H.
Owen, Liz
Johnston, Jennifer
Silveri, Marisa M.
Gensler, Marysia
Faulkner, Carol L.
Mann, Cathy
Wixted, Mary
Hernon, Anne Marie
Nyer, Maren B.
Brown, E. Richard P.
Jensen, John E.
author_sort Streeter, Chris C.
collection PubMed
description Objectives: The aims of this study were to assess the effects of an intervention of Iyengar yoga and coherent breathing at five breaths per minute on depressive symptoms and to determine optimal intervention yoga dosing for future studies in individuals with major depressive disorder (MDD). Methods: Subjects were randomized to the high-dose group (HDG) or low-dose group (LDG) for a 12-week intervention of three or two intervention classes per week, respectively. Eligible subjects were 18–64 years old with MDD, had baseline Beck Depression Inventory-II (BDI-II) scores ≥14, and were either on no antidepressant medications or on a stable dose of antidepressants for ≥3 months. The intervention included 90-min classes plus homework. Outcome measures were BDI-II scores and intervention compliance. Results: Fifteen HDG (M(age)=38.4±15.1 years) and 15 LDG (M(age)=34.7±10.4 years) subjects completed the intervention. BDI-II scores at screening and compliance did not differ between groups (p=0.26). BDI-II scores declined significantly from screening (24.6±1.7) to week 12 (6.0±3.8) for the HDG (–18.6±6.6; p < 0.001), and from screening (27.7±2.1) to week 12 (10.1±7.9) in the LDG (–17.7±9.3; p < 0.001). There were no significant differences between groups, based on response (i.e., >50% decrease in BDI-II scores; p=0.65) for the HDG (13/15 subjects) and LDG (11/15 subjects) or remission (i.e., number of subjects with BDI-II scores <14; p=1.00) for the HDG (14/15 subjects) and LDG (13/15 subjects) after the 12-week intervention, although a greater number of subjects in the HDG had 12-week BDI-II scores ≤10 (p=0.04). Conclusion: During this 12-week intervention of yoga plus coherent breathing, depressive symptoms declined significantly in patients with MDD in both the HDG and LDG. Both groups showed comparable compliance and clinical improvements, with more subjects in the HDG exhibiting BDI-II scores ≤10 at week 12.
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spelling pubmed-57179962017-12-06 Treatment of Major Depressive Disorder with Iyengar Yoga and Coherent Breathing: A Randomized Controlled Dosing Study Streeter, Chris C. Gerbarg, Patricia L. Whitfield, Theodore H. Owen, Liz Johnston, Jennifer Silveri, Marisa M. Gensler, Marysia Faulkner, Carol L. Mann, Cathy Wixted, Mary Hernon, Anne Marie Nyer, Maren B. Brown, E. Richard P. Jensen, John E. Altern Complement Ther Article Objectives: The aims of this study were to assess the effects of an intervention of Iyengar yoga and coherent breathing at five breaths per minute on depressive symptoms and to determine optimal intervention yoga dosing for future studies in individuals with major depressive disorder (MDD). Methods: Subjects were randomized to the high-dose group (HDG) or low-dose group (LDG) for a 12-week intervention of three or two intervention classes per week, respectively. Eligible subjects were 18–64 years old with MDD, had baseline Beck Depression Inventory-II (BDI-II) scores ≥14, and were either on no antidepressant medications or on a stable dose of antidepressants for ≥3 months. The intervention included 90-min classes plus homework. Outcome measures were BDI-II scores and intervention compliance. Results: Fifteen HDG (M(age)=38.4±15.1 years) and 15 LDG (M(age)=34.7±10.4 years) subjects completed the intervention. BDI-II scores at screening and compliance did not differ between groups (p=0.26). BDI-II scores declined significantly from screening (24.6±1.7) to week 12 (6.0±3.8) for the HDG (–18.6±6.6; p < 0.001), and from screening (27.7±2.1) to week 12 (10.1±7.9) in the LDG (–17.7±9.3; p < 0.001). There were no significant differences between groups, based on response (i.e., >50% decrease in BDI-II scores; p=0.65) for the HDG (13/15 subjects) and LDG (11/15 subjects) or remission (i.e., number of subjects with BDI-II scores <14; p=1.00) for the HDG (14/15 subjects) and LDG (13/15 subjects) after the 12-week intervention, although a greater number of subjects in the HDG had 12-week BDI-II scores ≤10 (p=0.04). Conclusion: During this 12-week intervention of yoga plus coherent breathing, depressive symptoms declined significantly in patients with MDD in both the HDG and LDG. Both groups showed comparable compliance and clinical improvements, with more subjects in the HDG exhibiting BDI-II scores ≤10 at week 12. Mary Ann Liebert, Inc. 2017-12-01 2017-12-01 /pmc/articles/PMC5717996/ /pubmed/29225455 http://dx.doi.org/10.1089/act.2017.29134.ccs Text en © Chris C. Streeter et al., 2017; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Article
Streeter, Chris C.
Gerbarg, Patricia L.
Whitfield, Theodore H.
Owen, Liz
Johnston, Jennifer
Silveri, Marisa M.
Gensler, Marysia
Faulkner, Carol L.
Mann, Cathy
Wixted, Mary
Hernon, Anne Marie
Nyer, Maren B.
Brown, E. Richard P.
Jensen, John E.
Treatment of Major Depressive Disorder with Iyengar Yoga and Coherent Breathing: A Randomized Controlled Dosing Study
title Treatment of Major Depressive Disorder with Iyengar Yoga and Coherent Breathing: A Randomized Controlled Dosing Study
title_full Treatment of Major Depressive Disorder with Iyengar Yoga and Coherent Breathing: A Randomized Controlled Dosing Study
title_fullStr Treatment of Major Depressive Disorder with Iyengar Yoga and Coherent Breathing: A Randomized Controlled Dosing Study
title_full_unstemmed Treatment of Major Depressive Disorder with Iyengar Yoga and Coherent Breathing: A Randomized Controlled Dosing Study
title_short Treatment of Major Depressive Disorder with Iyengar Yoga and Coherent Breathing: A Randomized Controlled Dosing Study
title_sort treatment of major depressive disorder with iyengar yoga and coherent breathing: a randomized controlled dosing study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5717996/
https://www.ncbi.nlm.nih.gov/pubmed/29225455
http://dx.doi.org/10.1089/act.2017.29134.ccs
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