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Decreased expression of the β(2) integrin on tumor cells is associated with a reduction in liver metastasis of colorectal cancer in mice

BACKGROUND: Lymphocyte Function-Associated Antigen-1 (LFA-1; CD18/CD11a) is one of the main adhesion molecules used by immune cells to infiltrate the liver under inflammatory conditions. Recently, the expression of this integrin has also been reported on several solid tumors, including colorectal ca...

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Detalles Bibliográficos
Autores principales: Benedicto, Aitor, Marquez, Joana, Herrero, Alba, Olaso, Elvira, Kolaczkowska, Elzbieta, Arteta, Beatriz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718006/
https://www.ncbi.nlm.nih.gov/pubmed/29207960
http://dx.doi.org/10.1186/s12885-017-3823-2