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Decreased expression of the β(2) integrin on tumor cells is associated with a reduction in liver metastasis of colorectal cancer in mice
BACKGROUND: Lymphocyte Function-Associated Antigen-1 (LFA-1; CD18/CD11a) is one of the main adhesion molecules used by immune cells to infiltrate the liver under inflammatory conditions. Recently, the expression of this integrin has also been reported on several solid tumors, including colorectal ca...
Autores principales: | Benedicto, Aitor, Marquez, Joana, Herrero, Alba, Olaso, Elvira, Kolaczkowska, Elzbieta, Arteta, Beatriz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718006/ https://www.ncbi.nlm.nih.gov/pubmed/29207960 http://dx.doi.org/10.1186/s12885-017-3823-2 |
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