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Gene gravity-like algorithm for disease gene prediction based on phenotype-specific network
BACKGROUND: Polygenic diseases are usually caused by the dysfunction of multiple genes. Unravelling such disease genes is crucial to fully understand the genetic landscape of diseases on molecular level. With the advent of ‘omic’ data era, network-based methods have prominently boosted disease gene...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718078/ https://www.ncbi.nlm.nih.gov/pubmed/29212543 http://dx.doi.org/10.1186/s12918-017-0519-9 |