Inflammasome-driven catecholamine catabolism in macrophages blunts lipolysis in the aged

Catecholamine-induced lipolysis, the first step in generation of energy substrates through hydrolysis of triglycerides (TGs) (1), declines with age (2,3). The defect in mobilization of free fatty acids (FFA) in elderly is accompanied with increased visceral adiposity, lower exercise capacity, failur...

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Detalles Bibliográficos
Autores principales: Camell, Christina D., Sander, Jil, Spadaro, Olga, Lee, Aileen, Nguyen, Kim Y., Wing, Allison, Goldberg, Emily L., Youm, Yun-Hee, Brown, Chester W., Elsworth, John, Rodeheffer, Matthew S., Schultze, Joachim L., Dixit, Vishwa Deep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149/
https://www.ncbi.nlm.nih.gov/pubmed/28953873
http://dx.doi.org/10.1038/nature24022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718149/
https://www.ncbi.nlm.nih.gov/pubmed/28953873
http://dx.doi.org/10.1038/nature24022

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