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A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets
Prolonged treatment execution time is a concern in CyberKnife robotic radiosurgery. Beam reduction and node reduction technique, and monitor unit optimization methods are adopted to reduce the treatment time. Usage of single collimator in the CyberKnife treatment plan can potentially reduce collimat...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718220/ https://www.ncbi.nlm.nih.gov/pubmed/22955653 http://dx.doi.org/10.1120/jacmp.v13i5.3864 |
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author | Harikrishnaperumal, Sudahar Kurup, Gopalakrishna Venkatraman, Murali Jagadeesan, Velmurugan |
author_facet | Harikrishnaperumal, Sudahar Kurup, Gopalakrishna Venkatraman, Murali Jagadeesan, Velmurugan |
author_sort | Harikrishnaperumal, Sudahar |
collection | PubMed |
description | Prolonged treatment execution time is a concern in CyberKnife robotic radiosurgery. Beam reduction and node reduction technique, and monitor unit optimization methods are adopted to reduce the treatment time. Usage of single collimator in the CyberKnife treatment plan can potentially reduce collimator exchange time. An optimal single collimator, which yields an acceptable dose distribution along with minimum number of nodes, beams, and monitor units, can be a versatile alternative for shortening treatment time. The aim of the present study is to find the optimal single collimator in CyberKnife treatment planning to shorten the treatment time with the acceptable dose distribution. A spherical planning target volume PTV1 was drawn in an anthropomorphic head and neck phantom. Plans with same treatment goals were generated for all the 12 collimators independently. [Formula: see text] was selected as the prescribing isodose and the prescribed dose was 10 Gy. The plan of the optimal collimator size was evaluated for conformity, homogeneity, and dose spillage outside the target. The optimum collimator size and the target dimensions were correlated. The study was repeated with two other target volumes PTV2 and PTV3 for generalizing the results. Collimator sizes just above the diameter of the spherical PTVs were yielding least number of nodes and beams with acceptable dose distributions. The collimator size of 35 mm is optimum for the PTV1, whose diameter is 31.4 mm. Similarly, 50 mm collimator is optimum for PTV2 [Formula: see text] and 20 mm collimator is optimum for PTV3 [Formula: see text]. The total number of monitor units is found to reduce with increasing collimator size. Optimal single collimator is found to be useful for shortening the treatment time in spherical targets. Studies on two clinical targets, (a brain metastasis and a liver metastasis cases) show comparable results with the phantom study. PACS numbers: 87.55.D, 87.55.de, 87.53.Ly, 87.55.kh, 87.56.nk, 87.55.ne, 87.55.‐x |
format | Online Article Text |
id | pubmed-5718220 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-57182202018-04-02 A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets Harikrishnaperumal, Sudahar Kurup, Gopalakrishna Venkatraman, Murali Jagadeesan, Velmurugan J Appl Clin Med Phys Radiation Oncology Physics Prolonged treatment execution time is a concern in CyberKnife robotic radiosurgery. Beam reduction and node reduction technique, and monitor unit optimization methods are adopted to reduce the treatment time. Usage of single collimator in the CyberKnife treatment plan can potentially reduce collimator exchange time. An optimal single collimator, which yields an acceptable dose distribution along with minimum number of nodes, beams, and monitor units, can be a versatile alternative for shortening treatment time. The aim of the present study is to find the optimal single collimator in CyberKnife treatment planning to shorten the treatment time with the acceptable dose distribution. A spherical planning target volume PTV1 was drawn in an anthropomorphic head and neck phantom. Plans with same treatment goals were generated for all the 12 collimators independently. [Formula: see text] was selected as the prescribing isodose and the prescribed dose was 10 Gy. The plan of the optimal collimator size was evaluated for conformity, homogeneity, and dose spillage outside the target. The optimum collimator size and the target dimensions were correlated. The study was repeated with two other target volumes PTV2 and PTV3 for generalizing the results. Collimator sizes just above the diameter of the spherical PTVs were yielding least number of nodes and beams with acceptable dose distributions. The collimator size of 35 mm is optimum for the PTV1, whose diameter is 31.4 mm. Similarly, 50 mm collimator is optimum for PTV2 [Formula: see text] and 20 mm collimator is optimum for PTV3 [Formula: see text]. The total number of monitor units is found to reduce with increasing collimator size. Optimal single collimator is found to be useful for shortening the treatment time in spherical targets. Studies on two clinical targets, (a brain metastasis and a liver metastasis cases) show comparable results with the phantom study. PACS numbers: 87.55.D, 87.55.de, 87.53.Ly, 87.55.kh, 87.56.nk, 87.55.ne, 87.55.‐x John Wiley and Sons Inc. 2012-09-06 /pmc/articles/PMC5718220/ /pubmed/22955653 http://dx.doi.org/10.1120/jacmp.v13i5.3864 Text en © 2012 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Oncology Physics Harikrishnaperumal, Sudahar Kurup, Gopalakrishna Venkatraman, Murali Jagadeesan, Velmurugan A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets |
title | A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets |
title_full | A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets |
title_fullStr | A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets |
title_full_unstemmed | A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets |
title_short | A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets |
title_sort | phantom study to determine the optimum size of a single collimator for shortening the treatment time in cyberknife stereotactic radiosurgery of spherical targets |
topic | Radiation Oncology Physics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718220/ https://www.ncbi.nlm.nih.gov/pubmed/22955653 http://dx.doi.org/10.1120/jacmp.v13i5.3864 |
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