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A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets

Prolonged treatment execution time is a concern in CyberKnife robotic radiosurgery. Beam reduction and node reduction technique, and monitor unit optimization methods are adopted to reduce the treatment time. Usage of single collimator in the CyberKnife treatment plan can potentially reduce collimat...

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Autores principales: Harikrishnaperumal, Sudahar, Kurup, Gopalakrishna, Venkatraman, Murali, Jagadeesan, Velmurugan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718220/
https://www.ncbi.nlm.nih.gov/pubmed/22955653
http://dx.doi.org/10.1120/jacmp.v13i5.3864
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author Harikrishnaperumal, Sudahar
Kurup, Gopalakrishna
Venkatraman, Murali
Jagadeesan, Velmurugan
author_facet Harikrishnaperumal, Sudahar
Kurup, Gopalakrishna
Venkatraman, Murali
Jagadeesan, Velmurugan
author_sort Harikrishnaperumal, Sudahar
collection PubMed
description Prolonged treatment execution time is a concern in CyberKnife robotic radiosurgery. Beam reduction and node reduction technique, and monitor unit optimization methods are adopted to reduce the treatment time. Usage of single collimator in the CyberKnife treatment plan can potentially reduce collimator exchange time. An optimal single collimator, which yields an acceptable dose distribution along with minimum number of nodes, beams, and monitor units, can be a versatile alternative for shortening treatment time. The aim of the present study is to find the optimal single collimator in CyberKnife treatment planning to shorten the treatment time with the acceptable dose distribution. A spherical planning target volume PTV1 was drawn in an anthropomorphic head and neck phantom. Plans with same treatment goals were generated for all the 12 collimators independently. [Formula: see text] was selected as the prescribing isodose and the prescribed dose was 10 Gy. The plan of the optimal collimator size was evaluated for conformity, homogeneity, and dose spillage outside the target. The optimum collimator size and the target dimensions were correlated. The study was repeated with two other target volumes PTV2 and PTV3 for generalizing the results. Collimator sizes just above the diameter of the spherical PTVs were yielding least number of nodes and beams with acceptable dose distributions. The collimator size of 35 mm is optimum for the PTV1, whose diameter is 31.4 mm. Similarly, 50 mm collimator is optimum for PTV2 [Formula: see text] and 20 mm collimator is optimum for PTV3 [Formula: see text]. The total number of monitor units is found to reduce with increasing collimator size. Optimal single collimator is found to be useful for shortening the treatment time in spherical targets. Studies on two clinical targets, (a brain metastasis and a liver metastasis cases) show comparable results with the phantom study. PACS numbers: 87.55.D, 87.55.de, 87.53.Ly, 87.55.kh, 87.56.nk, 87.55.ne, 87.55.‐x
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spelling pubmed-57182202018-04-02 A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets Harikrishnaperumal, Sudahar Kurup, Gopalakrishna Venkatraman, Murali Jagadeesan, Velmurugan J Appl Clin Med Phys Radiation Oncology Physics Prolonged treatment execution time is a concern in CyberKnife robotic radiosurgery. Beam reduction and node reduction technique, and monitor unit optimization methods are adopted to reduce the treatment time. Usage of single collimator in the CyberKnife treatment plan can potentially reduce collimator exchange time. An optimal single collimator, which yields an acceptable dose distribution along with minimum number of nodes, beams, and monitor units, can be a versatile alternative for shortening treatment time. The aim of the present study is to find the optimal single collimator in CyberKnife treatment planning to shorten the treatment time with the acceptable dose distribution. A spherical planning target volume PTV1 was drawn in an anthropomorphic head and neck phantom. Plans with same treatment goals were generated for all the 12 collimators independently. [Formula: see text] was selected as the prescribing isodose and the prescribed dose was 10 Gy. The plan of the optimal collimator size was evaluated for conformity, homogeneity, and dose spillage outside the target. The optimum collimator size and the target dimensions were correlated. The study was repeated with two other target volumes PTV2 and PTV3 for generalizing the results. Collimator sizes just above the diameter of the spherical PTVs were yielding least number of nodes and beams with acceptable dose distributions. The collimator size of 35 mm is optimum for the PTV1, whose diameter is 31.4 mm. Similarly, 50 mm collimator is optimum for PTV2 [Formula: see text] and 20 mm collimator is optimum for PTV3 [Formula: see text]. The total number of monitor units is found to reduce with increasing collimator size. Optimal single collimator is found to be useful for shortening the treatment time in spherical targets. Studies on two clinical targets, (a brain metastasis and a liver metastasis cases) show comparable results with the phantom study. PACS numbers: 87.55.D, 87.55.de, 87.53.Ly, 87.55.kh, 87.56.nk, 87.55.ne, 87.55.‐x John Wiley and Sons Inc. 2012-09-06 /pmc/articles/PMC5718220/ /pubmed/22955653 http://dx.doi.org/10.1120/jacmp.v13i5.3864 Text en © 2012 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Harikrishnaperumal, Sudahar
Kurup, Gopalakrishna
Venkatraman, Murali
Jagadeesan, Velmurugan
A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets
title A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets
title_full A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets
title_fullStr A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets
title_full_unstemmed A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets
title_short A phantom study to determine the optimum size of a single collimator for shortening the treatment time in CyberKnife stereotactic radiosurgery of spherical targets
title_sort phantom study to determine the optimum size of a single collimator for shortening the treatment time in cyberknife stereotactic radiosurgery of spherical targets
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718220/
https://www.ncbi.nlm.nih.gov/pubmed/22955653
http://dx.doi.org/10.1120/jacmp.v13i5.3864
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