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Surface dose reduction from bone interface in kilovoltage X‐ray radiation therapy: a Monte Carlo study of photon spectra

This study evaluated the dosimetric impact of surface dose reduction due to the loss of backscatter from the bone interface in kilovoltage (kV) X‐ray radiation therapy. Monte Carlo simulation was carried out using the EGSnrc code. An inhomogeneous phantom containing a thin water layer (0.5–5 mm) on...

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Autores principales: Chow, James C. L., Owrangi, Amir M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718228/
https://www.ncbi.nlm.nih.gov/pubmed/22955657
http://dx.doi.org/10.1120/jacmp.v13i5.3911
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author Chow, James C. L.
Owrangi, Amir M.
author_facet Chow, James C. L.
Owrangi, Amir M.
author_sort Chow, James C. L.
collection PubMed
description This study evaluated the dosimetric impact of surface dose reduction due to the loss of backscatter from the bone interface in kilovoltage (kV) X‐ray radiation therapy. Monte Carlo simulation was carried out using the EGSnrc code. An inhomogeneous phantom containing a thin water layer (0.5–5 mm) on top of a bone [Formula: see text] was irradiated by a clinical 105 kVp photon beam produced by a Gulmay D3225 X‐ray machine. Field sizes of 2, 5, and 10 cm diameter and source‐to‐surface distance of 20 cm were used. Surface doses for different phantom configurations were calculated using the DOSXYZnrc code. Photon energy spectra at the phantom surface and bone were determined according to the phase‐space files at the particle scoring planes which included the multiple crossers. For comparison, all Monte Carlo simulations were repeated in a phantom with the bone replaced by water. Surface dose reduction was found when a bone was underneath the water layer. When the water thickness was equal to 1 mm for the circular field of 5 cm diameter, a surface dose reduction of 6.3% was found. The dose reduction decreased to 4.7% and 3.4% when the water thickness increased to 3 and 5 mm, respectively. This shows that the impact of the surface dose uncertainty decreased while the water thickness over the bone increased. This result was supported by the decrease in relative intensity of the lower energy photons in the energy spectrum when the water layer was with and over the bone, compared to without the bone. We concluded that surface dose reduction of 7.8%–1.1% was found when the water thickness increased from 0.5–5 mm for circular fields with diameters ranging from 2–10 cm. This decrease of surface dose results in an overestimation of prescribed dose at the patient's surface, and might be a concern when using kV photon beam to treat skin tumors in sites such as forehead, chest wall, and kneecap. PACS number: 87.55.K‐; 87.55.ne; 87.57.uq
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spelling pubmed-57182282018-04-02 Surface dose reduction from bone interface in kilovoltage X‐ray radiation therapy: a Monte Carlo study of photon spectra Chow, James C. L. Owrangi, Amir M. J Appl Clin Med Phys Radiation Oncology Physics This study evaluated the dosimetric impact of surface dose reduction due to the loss of backscatter from the bone interface in kilovoltage (kV) X‐ray radiation therapy. Monte Carlo simulation was carried out using the EGSnrc code. An inhomogeneous phantom containing a thin water layer (0.5–5 mm) on top of a bone [Formula: see text] was irradiated by a clinical 105 kVp photon beam produced by a Gulmay D3225 X‐ray machine. Field sizes of 2, 5, and 10 cm diameter and source‐to‐surface distance of 20 cm were used. Surface doses for different phantom configurations were calculated using the DOSXYZnrc code. Photon energy spectra at the phantom surface and bone were determined according to the phase‐space files at the particle scoring planes which included the multiple crossers. For comparison, all Monte Carlo simulations were repeated in a phantom with the bone replaced by water. Surface dose reduction was found when a bone was underneath the water layer. When the water thickness was equal to 1 mm for the circular field of 5 cm diameter, a surface dose reduction of 6.3% was found. The dose reduction decreased to 4.7% and 3.4% when the water thickness increased to 3 and 5 mm, respectively. This shows that the impact of the surface dose uncertainty decreased while the water thickness over the bone increased. This result was supported by the decrease in relative intensity of the lower energy photons in the energy spectrum when the water layer was with and over the bone, compared to without the bone. We concluded that surface dose reduction of 7.8%–1.1% was found when the water thickness increased from 0.5–5 mm for circular fields with diameters ranging from 2–10 cm. This decrease of surface dose results in an overestimation of prescribed dose at the patient's surface, and might be a concern when using kV photon beam to treat skin tumors in sites such as forehead, chest wall, and kneecap. PACS number: 87.55.K‐; 87.55.ne; 87.57.uq John Wiley and Sons Inc. 2012-09-06 /pmc/articles/PMC5718228/ /pubmed/22955657 http://dx.doi.org/10.1120/jacmp.v13i5.3911 Text en © 2012 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Chow, James C. L.
Owrangi, Amir M.
Surface dose reduction from bone interface in kilovoltage X‐ray radiation therapy: a Monte Carlo study of photon spectra
title Surface dose reduction from bone interface in kilovoltage X‐ray radiation therapy: a Monte Carlo study of photon spectra
title_full Surface dose reduction from bone interface in kilovoltage X‐ray radiation therapy: a Monte Carlo study of photon spectra
title_fullStr Surface dose reduction from bone interface in kilovoltage X‐ray radiation therapy: a Monte Carlo study of photon spectra
title_full_unstemmed Surface dose reduction from bone interface in kilovoltage X‐ray radiation therapy: a Monte Carlo study of photon spectra
title_short Surface dose reduction from bone interface in kilovoltage X‐ray radiation therapy: a Monte Carlo study of photon spectra
title_sort surface dose reduction from bone interface in kilovoltage x‐ray radiation therapy: a monte carlo study of photon spectra
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718228/
https://www.ncbi.nlm.nih.gov/pubmed/22955657
http://dx.doi.org/10.1120/jacmp.v13i5.3911
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