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Evaluation of the efficiency and effectiveness of independent dose calculation followed by machine log file analysis against conventional measurement based IMRT QA

Experimental methods are commonly used for patient‐specific IMRT delivery verification. There are a variety of IMRT QA techniques which have been proposed and clinically used with a common understanding that not one single method can detect all possible errors. The aim of this work was to compare th...

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Autores principales: Sun, Baozhou, Rangaraj, Dharanipathy, Boddu, Sunita, Goddu, Murty, Yang, Deshan, Palaniswaamy, Geethpriya, Yaddanapudi, Sridhar, Wooten, Omar, Mutic, Sasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718232/
https://www.ncbi.nlm.nih.gov/pubmed/22955649
http://dx.doi.org/10.1120/jacmp.v13i5.3837
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author Sun, Baozhou
Rangaraj, Dharanipathy
Boddu, Sunita
Goddu, Murty
Yang, Deshan
Palaniswaamy, Geethpriya
Yaddanapudi, Sridhar
Wooten, Omar
Mutic, Sasa
author_facet Sun, Baozhou
Rangaraj, Dharanipathy
Boddu, Sunita
Goddu, Murty
Yang, Deshan
Palaniswaamy, Geethpriya
Yaddanapudi, Sridhar
Wooten, Omar
Mutic, Sasa
author_sort Sun, Baozhou
collection PubMed
description Experimental methods are commonly used for patient‐specific IMRT delivery verification. There are a variety of IMRT QA techniques which have been proposed and clinically used with a common understanding that not one single method can detect all possible errors. The aim of this work was to compare the efficiency and effectiveness of independent dose calculation followed by machine log file analysis to conventional measurement‐based methods in detecting errors in IMRT delivery. Sixteen IMRT treatment plans (5 head‐and‐neck, 3 rectum, 3 breast, and 5 prostate plans) created with a commercial treatment planning system (TPS) were recalculated on a QA phantom. All treatment plans underwent ion chamber (IC) and 2D diode array measurements. The same set of plans was also recomputed with another commercial treatment planning system and the two sets of calculations were compared. The deviations between dosimetric measurements and independent dose calculation were evaluated. The comparisons included evaluations of DVHs and point doses calculated by the two TPS systems. Machine log files were captured during pretreatment composite point dose measurements and analyzed to verify data transfer and performance of the delivery machine. Average deviation between IC measurements and point dose calculations with the two TPSs for head‐and‐neck plans were [Formula: see text] and [Formula: see text] , respectively. For 2D diode array measurements, the mean gamma value with 3% dose difference and 3 mm distance‐to‐agreement was within 1.5% for 13 of 16 plans. The mean 3D dose differences calculated from two TPSs were within 3% for head‐and‐neck cases and within 2% for other plans. The machine log file analysis showed that the gantry angle, jaw position, collimator angle, and MUs were consistent as planned, and maximal MLC position error was less than 0.5 mm. The independent dose calculation followed by the machine log analysis takes an average [Formula: see text] , while the experimental approach (using IC and 2D diode array measurements) takes an average about 2 hours in our clinic. Independent dose calculation followed by machine log file analysis can be a reliable tool to verify IMRT treatments. Additionally, independent dose calculations have the potential to identify several problems (heterogeneity calculations, data corruptions, system failures) with the primary TPS, which generally are not identifiable with a measurement‐based approach. Additionally, machine log file analysis can identify many problems (gantry, collimator, jaw setting) which also may not be detected with a measurement‐based approach. Machine log file analysis could also detect performance problems for individual MLC leaves which could be masked in the analysis of a measured fluence. PACS numbers: 87.53.Bn, 87.55.Qr, 87.55.km, 87.57.Uq
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spelling pubmed-57182322018-04-02 Evaluation of the efficiency and effectiveness of independent dose calculation followed by machine log file analysis against conventional measurement based IMRT QA Sun, Baozhou Rangaraj, Dharanipathy Boddu, Sunita Goddu, Murty Yang, Deshan Palaniswaamy, Geethpriya Yaddanapudi, Sridhar Wooten, Omar Mutic, Sasa J Appl Clin Med Phys Radiation Oncology Physics Experimental methods are commonly used for patient‐specific IMRT delivery verification. There are a variety of IMRT QA techniques which have been proposed and clinically used with a common understanding that not one single method can detect all possible errors. The aim of this work was to compare the efficiency and effectiveness of independent dose calculation followed by machine log file analysis to conventional measurement‐based methods in detecting errors in IMRT delivery. Sixteen IMRT treatment plans (5 head‐and‐neck, 3 rectum, 3 breast, and 5 prostate plans) created with a commercial treatment planning system (TPS) were recalculated on a QA phantom. All treatment plans underwent ion chamber (IC) and 2D diode array measurements. The same set of plans was also recomputed with another commercial treatment planning system and the two sets of calculations were compared. The deviations between dosimetric measurements and independent dose calculation were evaluated. The comparisons included evaluations of DVHs and point doses calculated by the two TPS systems. Machine log files were captured during pretreatment composite point dose measurements and analyzed to verify data transfer and performance of the delivery machine. Average deviation between IC measurements and point dose calculations with the two TPSs for head‐and‐neck plans were [Formula: see text] and [Formula: see text] , respectively. For 2D diode array measurements, the mean gamma value with 3% dose difference and 3 mm distance‐to‐agreement was within 1.5% for 13 of 16 plans. The mean 3D dose differences calculated from two TPSs were within 3% for head‐and‐neck cases and within 2% for other plans. The machine log file analysis showed that the gantry angle, jaw position, collimator angle, and MUs were consistent as planned, and maximal MLC position error was less than 0.5 mm. The independent dose calculation followed by the machine log analysis takes an average [Formula: see text] , while the experimental approach (using IC and 2D diode array measurements) takes an average about 2 hours in our clinic. Independent dose calculation followed by machine log file analysis can be a reliable tool to verify IMRT treatments. Additionally, independent dose calculations have the potential to identify several problems (heterogeneity calculations, data corruptions, system failures) with the primary TPS, which generally are not identifiable with a measurement‐based approach. Additionally, machine log file analysis can identify many problems (gantry, collimator, jaw setting) which also may not be detected with a measurement‐based approach. Machine log file analysis could also detect performance problems for individual MLC leaves which could be masked in the analysis of a measured fluence. PACS numbers: 87.53.Bn, 87.55.Qr, 87.55.km, 87.57.Uq John Wiley and Sons Inc. 2012-09-06 /pmc/articles/PMC5718232/ /pubmed/22955649 http://dx.doi.org/10.1120/jacmp.v13i5.3837 Text en © 2012 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Sun, Baozhou
Rangaraj, Dharanipathy
Boddu, Sunita
Goddu, Murty
Yang, Deshan
Palaniswaamy, Geethpriya
Yaddanapudi, Sridhar
Wooten, Omar
Mutic, Sasa
Evaluation of the efficiency and effectiveness of independent dose calculation followed by machine log file analysis against conventional measurement based IMRT QA
title Evaluation of the efficiency and effectiveness of independent dose calculation followed by machine log file analysis against conventional measurement based IMRT QA
title_full Evaluation of the efficiency and effectiveness of independent dose calculation followed by machine log file analysis against conventional measurement based IMRT QA
title_fullStr Evaluation of the efficiency and effectiveness of independent dose calculation followed by machine log file analysis against conventional measurement based IMRT QA
title_full_unstemmed Evaluation of the efficiency and effectiveness of independent dose calculation followed by machine log file analysis against conventional measurement based IMRT QA
title_short Evaluation of the efficiency and effectiveness of independent dose calculation followed by machine log file analysis against conventional measurement based IMRT QA
title_sort evaluation of the efficiency and effectiveness of independent dose calculation followed by machine log file analysis against conventional measurement based imrt qa
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718232/
https://www.ncbi.nlm.nih.gov/pubmed/22955649
http://dx.doi.org/10.1120/jacmp.v13i5.3837
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