Correlation Between Methylenetetrahydrofolate Reductase (MTHFR) C677T Polymorphisms and Pemetrexed Chemotherapy Efficacy/Toxicity in Non-Squamous Non-Small Cell Lung Cancer

BACKGROUND: In the present study, we aimed to retrospectively analyze the correlation between toxicity of pemetrexed (PEM) chemotherapy and methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms in patients with advanced non-squamous non-small cell lung cancer (non-sq NSCLC). MATERIAL/METHO...

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Detalles Bibliográficos
Autores principales: Lan, Gaochen, Lin, Lin, Chen, Xiong, Chen, Libin, Chen, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Clinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718261/
https://www.ncbi.nlm.nih.gov/pubmed/29186089
http://dx.doi.org/10.12659/MSM.904836

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