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An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers

OBJECTIVES: The co-primary objectives of this study were to determine the human pharmacokinetics (PK) of oral NR and the effect of NR on whole blood nicotinamide adenine dinucleotide (NAD+) levels. BACKGROUND: Though mitochondrial dysfunction plays a critical role in the development and progression...

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Detalles Bibliográficos
Autores principales: Airhart, Sophia E., Shireman, Laura M., Risler, Linda J., Anderson, Gail D., Nagana Gowda, G. A., Raftery, Daniel, Tian, Rong, Shen, Danny D., O’Brien, Kevin D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718430/
https://www.ncbi.nlm.nih.gov/pubmed/29211728
http://dx.doi.org/10.1371/journal.pone.0186459