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An open-label, non-randomized study of the pharmacokinetics of the nutritional supplement nicotinamide riboside (NR) and its effects on blood NAD+ levels in healthy volunteers
OBJECTIVES: The co-primary objectives of this study were to determine the human pharmacokinetics (PK) of oral NR and the effect of NR on whole blood nicotinamide adenine dinucleotide (NAD+) levels. BACKGROUND: Though mitochondrial dysfunction plays a critical role in the development and progression...
Autores principales: | Airhart, Sophia E., Shireman, Laura M., Risler, Linda J., Anderson, Gail D., Nagana Gowda, G. A., Raftery, Daniel, Tian, Rong, Shen, Danny D., O’Brien, Kevin D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718430/ https://www.ncbi.nlm.nih.gov/pubmed/29211728 http://dx.doi.org/10.1371/journal.pone.0186459 |
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