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The influence of field size on stopping‐power ratios in‐ and out‐of‐field: quantitative data for the BrainLAB m3 micro‐multileaf collimator

The objective of this work is to quantify the systematic errors introduced by the common assumption of invariant secondary electron spectra with changing field sizes, as relevant to stereotactic radiotherapy and other treatment modes incorporating small beam segments delivered with a linac‐based ste...

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Autores principales: Taylor, M.L., Kairn, T., Kron, T., Dunn, L., Johnston, P.N., Franich, R.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718545/
https://www.ncbi.nlm.nih.gov/pubmed/23149796
http://dx.doi.org/10.1120/jacmp.v13i6.4019
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author Taylor, M.L.
Kairn, T.
Kron, T.
Dunn, L.
Johnston, P.N.
Franich, R.D.
author_facet Taylor, M.L.
Kairn, T.
Kron, T.
Dunn, L.
Johnston, P.N.
Franich, R.D.
author_sort Taylor, M.L.
collection PubMed
description The objective of this work is to quantify the systematic errors introduced by the common assumption of invariant secondary electron spectra with changing field sizes, as relevant to stereotactic radiotherapy and other treatment modes incorporating small beam segments delivered with a linac‐based stereotactic unit. The EGSnrc/BEAMnrc Monte Carlo radiation transport code was used to construct a dosimetrically‐matched model of a Varian 600C linear accelerator with mounted BrainLAB micro‐multileaf collimator. Stopping‐power ratios were calculated for field sizes ranging from [Formula: see text] up to the maximum ([Formula: see text]), and differences between these and the reference field were computed. Quantitative stopping power data for the BrainLAB micro‐multileaf collimator has been compiled. Field size dependent differences to reference conditions increase with decreasing field size and increasing depth, but remain a fraction of a percent for all field sizes studied. However, for dosimetry outside the primary field, errors induced by the assumption of invariant electron spectra can be greater than 1%, increasing with field size. It is also shown that simplification of the Spencer‐Attix formulation by ignoring secondary electrons below the cutoff kinetic energy applied to the integration results in underestimation of stopping‐power ratios of about 0.3% (and is independent of field size and depth). This work is the first to quantify stopping powers from a BrainLAB micro‐multileaf collimator. Many earlier studies model simplified beams, ignoring collimator scatter, which is shown to significantly influence the spectrum. Importantly, we have confirmed that the assumption of unchanging electron spectra with varying field sizes is justifiable when performing (typical) in‐field dosimetry of stereotactic fields. Clinicians and physicists undertaking precise out‐of‐field measurements for the purposes of risk estimation, ought to be aware that the more pronounced spectral variation results in stopping powers (and hence doses) that differ more than for in‐field dosimetry. PACS number: 87.10.RT; 87.53.Ly; 87.56.jf; 87.56.jk
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spelling pubmed-57185452018-04-02 The influence of field size on stopping‐power ratios in‐ and out‐of‐field: quantitative data for the BrainLAB m3 micro‐multileaf collimator Taylor, M.L. Kairn, T. Kron, T. Dunn, L. Johnston, P.N. Franich, R.D. J Appl Clin Med Phys Radiation Measurements The objective of this work is to quantify the systematic errors introduced by the common assumption of invariant secondary electron spectra with changing field sizes, as relevant to stereotactic radiotherapy and other treatment modes incorporating small beam segments delivered with a linac‐based stereotactic unit. The EGSnrc/BEAMnrc Monte Carlo radiation transport code was used to construct a dosimetrically‐matched model of a Varian 600C linear accelerator with mounted BrainLAB micro‐multileaf collimator. Stopping‐power ratios were calculated for field sizes ranging from [Formula: see text] up to the maximum ([Formula: see text]), and differences between these and the reference field were computed. Quantitative stopping power data for the BrainLAB micro‐multileaf collimator has been compiled. Field size dependent differences to reference conditions increase with decreasing field size and increasing depth, but remain a fraction of a percent for all field sizes studied. However, for dosimetry outside the primary field, errors induced by the assumption of invariant electron spectra can be greater than 1%, increasing with field size. It is also shown that simplification of the Spencer‐Attix formulation by ignoring secondary electrons below the cutoff kinetic energy applied to the integration results in underestimation of stopping‐power ratios of about 0.3% (and is independent of field size and depth). This work is the first to quantify stopping powers from a BrainLAB micro‐multileaf collimator. Many earlier studies model simplified beams, ignoring collimator scatter, which is shown to significantly influence the spectrum. Importantly, we have confirmed that the assumption of unchanging electron spectra with varying field sizes is justifiable when performing (typical) in‐field dosimetry of stereotactic fields. Clinicians and physicists undertaking precise out‐of‐field measurements for the purposes of risk estimation, ought to be aware that the more pronounced spectral variation results in stopping powers (and hence doses) that differ more than for in‐field dosimetry. PACS number: 87.10.RT; 87.53.Ly; 87.56.jf; 87.56.jk John Wiley and Sons Inc. 2012-11-08 /pmc/articles/PMC5718545/ /pubmed/23149796 http://dx.doi.org/10.1120/jacmp.v13i6.4019 Text en © 2012 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Measurements
Taylor, M.L.
Kairn, T.
Kron, T.
Dunn, L.
Johnston, P.N.
Franich, R.D.
The influence of field size on stopping‐power ratios in‐ and out‐of‐field: quantitative data for the BrainLAB m3 micro‐multileaf collimator
title The influence of field size on stopping‐power ratios in‐ and out‐of‐field: quantitative data for the BrainLAB m3 micro‐multileaf collimator
title_full The influence of field size on stopping‐power ratios in‐ and out‐of‐field: quantitative data for the BrainLAB m3 micro‐multileaf collimator
title_fullStr The influence of field size on stopping‐power ratios in‐ and out‐of‐field: quantitative data for the BrainLAB m3 micro‐multileaf collimator
title_full_unstemmed The influence of field size on stopping‐power ratios in‐ and out‐of‐field: quantitative data for the BrainLAB m3 micro‐multileaf collimator
title_short The influence of field size on stopping‐power ratios in‐ and out‐of‐field: quantitative data for the BrainLAB m3 micro‐multileaf collimator
title_sort influence of field size on stopping‐power ratios in‐ and out‐of‐field: quantitative data for the brainlab m3 micro‐multileaf collimator
topic Radiation Measurements
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718545/
https://www.ncbi.nlm.nih.gov/pubmed/23149796
http://dx.doi.org/10.1120/jacmp.v13i6.4019
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