How well do you know your mutation? Complex effects of genetic background on expressivity, complementation, and ordering of allelic effects

For a given gene, different mutations influence organismal phenotypes to varying degrees. However, the expressivity of these variants not only depends on the DNA lesion associated with the mutation, but also on factors including the genetic background and rearing environment. The degree to which the...

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Detalles Bibliográficos
Autores principales: Chandler, Christopher H., Chari, Sudarshan, Kowalski, Alycia, Choi, Lin, Tack, David, DeNieu, Michael, Pitchers, William, Sonnenschein, Anne, Marvin, Leslie, Hummel, Kristen, Marier, Christian, Victory, Andrew, Porter, Cody, Mammel, Anna, Holms, Julie, Sivaratnam, Gayatri, Dworkin, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718557/
https://www.ncbi.nlm.nih.gov/pubmed/29166655
http://dx.doi.org/10.1371/journal.pgen.1007075

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