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Interleukin-36γ and IL-36 receptor signaling mediate impaired host immunity and lung injury in cytotoxic Pseudomonas aeruginosa pulmonary infection: Role of prostaglandin E2
Pseudomonas aeruginosa is a Gram-negative pathogen that can lead to severe infection associated with lung injury and high mortality. The interleukin (IL)-36 cytokines (IL-36α, IL-36β and IL-36γ) are newly described IL-1 like family cytokines that promote inflammatory response via binding to the IL-3...
Autores principales: | Aoyagi, Tetsuji, Newstead, Michael W., Zeng, Xianying, Nanjo, Yuta, Peters-Golden, Marc, Kaku, Mitsuo, Standiford, Theodore J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718565/ https://www.ncbi.nlm.nih.gov/pubmed/29166668 http://dx.doi.org/10.1371/journal.ppat.1006737 |
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