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Image‐guided bolus electron conformal therapy – a case study

We report on our initial experience with daily image guidance for the treatment of a patient with a basal cell carcinoma of the nasal dorsum using bolus electron conformal therapy. We describe our approach to daily alignment using treatment machine‐integrated megavoltage (MV) planar imaging in conju...

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Autores principales: Zeidan, Omar A., Chauhan, Bhavin D., Estabrook, William W., Willoughby, Twyla R., Manon, Rafael R., Meeks, Sanford L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718591/
https://www.ncbi.nlm.nih.gov/pubmed/21330977
http://dx.doi.org/10.1120/jacmp.v12i1.3311
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author Zeidan, Omar A.
Chauhan, Bhavin D.
Estabrook, William W.
Willoughby, Twyla R.
Manon, Rafael R.
Meeks, Sanford L.
author_facet Zeidan, Omar A.
Chauhan, Bhavin D.
Estabrook, William W.
Willoughby, Twyla R.
Manon, Rafael R.
Meeks, Sanford L.
author_sort Zeidan, Omar A.
collection PubMed
description We report on our initial experience with daily image guidance for the treatment of a patient with a basal cell carcinoma of the nasal dorsum using bolus electron conformal therapy. We describe our approach to daily alignment using treatment machine‐integrated megavoltage (MV) planar imaging in conjunction with cone beam CT (CBCT) volumetric imaging to ensure the best possible setup reproducibility. Based on MV imaging, beam aperture misalignment with the intended treatment region was as large as 0.5 cm in the coronal plane. Four of the five fractions analyzed show induced shifts when compared to digitally reconstructed radiographs (DRR), in the range of [Formula: see text]. Daily inspection of CBCT images show that the bolus device can have significant tilt in any given direction by as much as 13° with respect to beam axis. In addition, we show that CBCT images reveal air gaps between bolus and skin that vary from day to day, and can potentially degrade surface dose coverage. Retrospective dose calculation on CBCT image sets shows that when daily shifts based on MV imaging are not corrected, geometrical miss of the planning target volume (PTV) can cause an underdosing as large as 14% based on DVH analysis of the dose to the 90% of the PTV volume. PACS number: 87.55.kh
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spelling pubmed-57185912018-04-02 Image‐guided bolus electron conformal therapy – a case study Zeidan, Omar A. Chauhan, Bhavin D. Estabrook, William W. Willoughby, Twyla R. Manon, Rafael R. Meeks, Sanford L. J Appl Clin Med Phys Radiation Oncology Physics We report on our initial experience with daily image guidance for the treatment of a patient with a basal cell carcinoma of the nasal dorsum using bolus electron conformal therapy. We describe our approach to daily alignment using treatment machine‐integrated megavoltage (MV) planar imaging in conjunction with cone beam CT (CBCT) volumetric imaging to ensure the best possible setup reproducibility. Based on MV imaging, beam aperture misalignment with the intended treatment region was as large as 0.5 cm in the coronal plane. Four of the five fractions analyzed show induced shifts when compared to digitally reconstructed radiographs (DRR), in the range of [Formula: see text]. Daily inspection of CBCT images show that the bolus device can have significant tilt in any given direction by as much as 13° with respect to beam axis. In addition, we show that CBCT images reveal air gaps between bolus and skin that vary from day to day, and can potentially degrade surface dose coverage. Retrospective dose calculation on CBCT image sets shows that when daily shifts based on MV imaging are not corrected, geometrical miss of the planning target volume (PTV) can cause an underdosing as large as 14% based on DVH analysis of the dose to the 90% of the PTV volume. PACS number: 87.55.kh John Wiley and Sons Inc. 2010-10-07 /pmc/articles/PMC5718591/ /pubmed/21330977 http://dx.doi.org/10.1120/jacmp.v12i1.3311 Text en © 2011 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Zeidan, Omar A.
Chauhan, Bhavin D.
Estabrook, William W.
Willoughby, Twyla R.
Manon, Rafael R.
Meeks, Sanford L.
Image‐guided bolus electron conformal therapy – a case study
title Image‐guided bolus electron conformal therapy – a case study
title_full Image‐guided bolus electron conformal therapy – a case study
title_fullStr Image‐guided bolus electron conformal therapy – a case study
title_full_unstemmed Image‐guided bolus electron conformal therapy – a case study
title_short Image‐guided bolus electron conformal therapy – a case study
title_sort image‐guided bolus electron conformal therapy – a case study
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718591/
https://www.ncbi.nlm.nih.gov/pubmed/21330977
http://dx.doi.org/10.1120/jacmp.v12i1.3311
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