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Feasibility of using respiratory correlated mega voltage cone beam computed tomography to measure tumor motion

The purpose of this study was to test the feasibility of using respiratory correlated mega voltage cone‐beam computed tomography (MVCBCT), taken during patient localization, to quantify the size and motion of lung tumors. An imaging phantom was constructed of a basswood frame embedded with six diffe...

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Autores principales: Chen, Mingqing, Siochi, R. Alfredo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718660/
https://www.ncbi.nlm.nih.gov/pubmed/21587196
http://dx.doi.org/10.1120/jacmp.v12i2.3473
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author Chen, Mingqing
Siochi, R. Alfredo
author_facet Chen, Mingqing
Siochi, R. Alfredo
author_sort Chen, Mingqing
collection PubMed
description The purpose of this study was to test the feasibility of using respiratory correlated mega voltage cone‐beam computed tomography (MVCBCT), taken during patient localization, to quantify the size and motion of lung tumors. An imaging phantom was constructed of a basswood frame embedded with six different‐sized spherical pieces of paraffin wax. The Quasar respiratory motion phantom was programmed to move the imaging phantom using typical respiratory motion. The moving imaging phantom was scanned using various MVCBCT imaging parameters, including two beam line types, two protocols with different ranges of rotation and different imaging doses. A static phantom was also imaged as a control. For all the 3D volumetric images, the contours of the six spherical inserts were measured manually. Compared with the nominal sphere diameter, the average relative error in the size of the respiratory correlated MVCBCT spheres ranged from 5.3% to 12.6% for the four largest spheres, ranging in size from 3.6 cc to 29 cc. Larger errors were recorded for the two smallest inserts. The average relative error in motion was 5.1% smaller than the programmed amplitude of 3.0 cm. We are able to conclude that it is feasible to use respiratory correlated MVCBCT to quantify tumor motion for lung cancer patients. PACS numbers: 87.19.Wx, 87.57.Q
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spelling pubmed-57186602018-04-02 Feasibility of using respiratory correlated mega voltage cone beam computed tomography to measure tumor motion Chen, Mingqing Siochi, R. Alfredo J Appl Clin Med Phys Radiation Oncology Physics The purpose of this study was to test the feasibility of using respiratory correlated mega voltage cone‐beam computed tomography (MVCBCT), taken during patient localization, to quantify the size and motion of lung tumors. An imaging phantom was constructed of a basswood frame embedded with six different‐sized spherical pieces of paraffin wax. The Quasar respiratory motion phantom was programmed to move the imaging phantom using typical respiratory motion. The moving imaging phantom was scanned using various MVCBCT imaging parameters, including two beam line types, two protocols with different ranges of rotation and different imaging doses. A static phantom was also imaged as a control. For all the 3D volumetric images, the contours of the six spherical inserts were measured manually. Compared with the nominal sphere diameter, the average relative error in the size of the respiratory correlated MVCBCT spheres ranged from 5.3% to 12.6% for the four largest spheres, ranging in size from 3.6 cc to 29 cc. Larger errors were recorded for the two smallest inserts. The average relative error in motion was 5.1% smaller than the programmed amplitude of 3.0 cm. We are able to conclude that it is feasible to use respiratory correlated MVCBCT to quantify tumor motion for lung cancer patients. PACS numbers: 87.19.Wx, 87.57.Q John Wiley and Sons Inc. 2011-01-31 /pmc/articles/PMC5718660/ /pubmed/21587196 http://dx.doi.org/10.1120/jacmp.v12i2.3473 Text en © 2011 The Authors. https://creativecommons.org/licenses/by/3.0/This is an open access article under the terms of the Creative Commons Attribution (https://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Radiation Oncology Physics
Chen, Mingqing
Siochi, R. Alfredo
Feasibility of using respiratory correlated mega voltage cone beam computed tomography to measure tumor motion
title Feasibility of using respiratory correlated mega voltage cone beam computed tomography to measure tumor motion
title_full Feasibility of using respiratory correlated mega voltage cone beam computed tomography to measure tumor motion
title_fullStr Feasibility of using respiratory correlated mega voltage cone beam computed tomography to measure tumor motion
title_full_unstemmed Feasibility of using respiratory correlated mega voltage cone beam computed tomography to measure tumor motion
title_short Feasibility of using respiratory correlated mega voltage cone beam computed tomography to measure tumor motion
title_sort feasibility of using respiratory correlated mega voltage cone beam computed tomography to measure tumor motion
topic Radiation Oncology Physics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718660/
https://www.ncbi.nlm.nih.gov/pubmed/21587196
http://dx.doi.org/10.1120/jacmp.v12i2.3473
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