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Estrogen Activation by Steroid Sulfatase Increases Colorectal Cancer Proliferation via GPER
CONTEXT: Estrogens affect the incidence and progression of colorectal cancer (CRC), although the precise molecular mechanisms remain ill-defined. OBJECTIVE: The present study investigated prereceptor estrogen metabolism through steroid sulphatase (STS) and 17β-hydroxysteroid dehydrogenase activity a...
Autores principales: | Gilligan, Lorna C., Rahman, Habibur P., Hewitt, Anne-Marie, Sitch, Alice J., Gondal, Ali, Arvaniti, Anastasia, Taylor, Angela E., Read, Martin L., Morton, Dion G., Foster, Paul A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Endocrine Society
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718700/ https://www.ncbi.nlm.nih.gov/pubmed/28945888 http://dx.doi.org/10.1210/jc.2016-3716 |
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