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Simultaneous enumeration of cancer and immune cell types from bulk tumor gene expression data

Immune cells infiltrating tumors can have important impact on tumor progression and response to therapy. We present an efficient algorithm to simultaneously estimate the fraction of cancer and immune cell types from bulk tumor gene expression data. Our method integrates novel gene expression profile...

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Detalles Bibliográficos
Autores principales:	Racle, Julien, de Jonge, Kaat, Baumgaertner, Petra, Speiser, Daniel E, Gfeller, David
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2017
Materias:	Cancer Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718706/ https://www.ncbi.nlm.nih.gov/pubmed/29130882 http://dx.doi.org/10.7554/eLife.26476

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