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Energy absorption buildup factors of human organs and tissues at energies and penetration depths relevant for radiotherapy and diagnostics
Energy absorption geometric progression (GP) fitting parameters and the corresponding buildup factors have been computed for human organs and tissues, such as adipose tissue, blood (whole), cortical bone, brain (grey/white matter), breast tissue, eye lens, lung tissue, skeletal muscle, ovary, testis...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718747/ https://www.ncbi.nlm.nih.gov/pubmed/22089011 http://dx.doi.org/10.1120/jacmp.v12i4.3557 |
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author | Manohara, S. R. Hanagodimath, S. M. Gerward, L. |
author_facet | Manohara, S. R. Hanagodimath, S. M. Gerward, L. |
author_sort | Manohara, S. R. |
collection | PubMed |
description | Energy absorption geometric progression (GP) fitting parameters and the corresponding buildup factors have been computed for human organs and tissues, such as adipose tissue, blood (whole), cortical bone, brain (grey/white matter), breast tissue, eye lens, lung tissue, skeletal muscle, ovary, testis, soft tissue, and soft tissue (4‐component), for the photon energy range 0.015–15 MeV and for penetration depths up to 40 mfp (mean free path). The chemical composition of human organs and tissues is seen to influence the energy absorption buildup factors. It is also found that the buildup factor of human organs and tissues changes significantly with the change of incident photon energy and effective atomic number, [Formula: see text]. These changes are due to the dominance of different photon interaction processes in different energy regions and different chemical compositions of human organs and tissues. With the proper knowledge of buildup factors of human organs and tissues, energy absorption in the human body can be carefully controlled. The present results will help in estimating safe dose levels for radiotherapy patients and also useful in diagnostics and dosimetry. The tissue‐equivalent materials for skeletal muscle, adipose tissue, cortical bone, and lung tissue are also discussed. It is observed that water and MS20 are good tissue equivalent materials for skeletal muscle in the extended energy range. PACS numbers: 32.80‐t, 87.53‐j, 78.70‐g, 78.70‐Ck |
format | Online Article Text |
id | pubmed-5718747 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | John Wiley and Sons Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-57187472018-04-02 Energy absorption buildup factors of human organs and tissues at energies and penetration depths relevant for radiotherapy and diagnostics Manohara, S. R. Hanagodimath, S. M. Gerward, L. J Appl Clin Med Phys Radiation Measurements Energy absorption geometric progression (GP) fitting parameters and the corresponding buildup factors have been computed for human organs and tissues, such as adipose tissue, blood (whole), cortical bone, brain (grey/white matter), breast tissue, eye lens, lung tissue, skeletal muscle, ovary, testis, soft tissue, and soft tissue (4‐component), for the photon energy range 0.015–15 MeV and for penetration depths up to 40 mfp (mean free path). The chemical composition of human organs and tissues is seen to influence the energy absorption buildup factors. It is also found that the buildup factor of human organs and tissues changes significantly with the change of incident photon energy and effective atomic number, [Formula: see text]. These changes are due to the dominance of different photon interaction processes in different energy regions and different chemical compositions of human organs and tissues. With the proper knowledge of buildup factors of human organs and tissues, energy absorption in the human body can be carefully controlled. The present results will help in estimating safe dose levels for radiotherapy patients and also useful in diagnostics and dosimetry. The tissue‐equivalent materials for skeletal muscle, adipose tissue, cortical bone, and lung tissue are also discussed. It is observed that water and MS20 are good tissue equivalent materials for skeletal muscle in the extended energy range. PACS numbers: 32.80‐t, 87.53‐j, 78.70‐g, 78.70‐Ck John Wiley and Sons Inc. 2011-11-15 /pmc/articles/PMC5718747/ /pubmed/22089011 http://dx.doi.org/10.1120/jacmp.v12i4.3557 Text en © 2011 The Authors. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/3.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Radiation Measurements Manohara, S. R. Hanagodimath, S. M. Gerward, L. Energy absorption buildup factors of human organs and tissues at energies and penetration depths relevant for radiotherapy and diagnostics |
title | Energy absorption buildup factors of human organs and tissues at energies and penetration depths relevant for radiotherapy and diagnostics |
title_full | Energy absorption buildup factors of human organs and tissues at energies and penetration depths relevant for radiotherapy and diagnostics |
title_fullStr | Energy absorption buildup factors of human organs and tissues at energies and penetration depths relevant for radiotherapy and diagnostics |
title_full_unstemmed | Energy absorption buildup factors of human organs and tissues at energies and penetration depths relevant for radiotherapy and diagnostics |
title_short | Energy absorption buildup factors of human organs and tissues at energies and penetration depths relevant for radiotherapy and diagnostics |
title_sort | energy absorption buildup factors of human organs and tissues at energies and penetration depths relevant for radiotherapy and diagnostics |
topic | Radiation Measurements |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718747/ https://www.ncbi.nlm.nih.gov/pubmed/22089011 http://dx.doi.org/10.1120/jacmp.v12i4.3557 |
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