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Application of replication-defective West Nile virus vector to non-flavivirus vaccine targets

The RepliVax vaccine platform(RV) is based on flavivirus genomes that are rationally attenuated by deletion. The self-limiting infection provided by RV has been demonstrated to be safe, highly immunogenic and efficacious for several vaccine candidates against flaviviruses. Here respiratory syncytial...

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Detalles Bibliográficos
Autores principales: Giel-Moloney, Maryann, Vaine, Michael, Zhang, Linong, Parrington, Mark, Gajewska, Beata, Vogel, Thorsten U., Pougatcheva, Svetlana O., Duan, Xiaochu, Farrell, Timothy, Ustyugova, Irina, Phogat, Sanjay, Kleanthous, Harry, Pugachev, Konstantin V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718821/
https://www.ncbi.nlm.nih.gov/pubmed/28925795
http://dx.doi.org/10.1080/21645515.2017.1373920