Protein kinase CK2 inhibition suppresses neointima formation via a proline-rich homeodomain-dependent mechanism

Neointimal hyperplasia is a product of VSMC replication and consequent accumulation within the blood vessel wall. In this study, we determined whether inhibition of protein kinase CK2 and the resultant stabilisation of proline-rich homeodomain (PRH) could suppress VSMC proliferation. Both silencing...

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Detalles Bibliográficos
Autores principales: Wadey, K.S., Brown, B.A., Sala-Newby, G.B., Jayaraman, P.-S., Gaston, K., George, S.J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718878/
https://www.ncbi.nlm.nih.gov/pubmed/28927755
http://dx.doi.org/10.1016/j.vph.2017.09.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718878/
https://www.ncbi.nlm.nih.gov/pubmed/28927755
http://dx.doi.org/10.1016/j.vph.2017.09.004

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