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Longer observation time increases adenoma detection in the proximal colon – a prospective study

BACKGROUND AND STUDY AIMS : Longer observation times are associated with increased adenoma detection rates (ADR) in the entire colon. However, adenomas in the proximal colon are at risk of being missed during colonoscopy. The aim of this study was to investigate the impact of observation time on det...

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Autores principales: Klare, Peter, Phlipsen, Henrik, Haller, Bernhard, Einwächter, Henrik, Weber, Andreas, Abdelhafez, Mohamed, Bajbouj, Monther, Brown, Hayley, Schmid, Roland M., von Delius, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: © Georg Thieme Verlag KG 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718907/
https://www.ncbi.nlm.nih.gov/pubmed/29218322
http://dx.doi.org/10.1055/s-0043-121072
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author Klare, Peter
Phlipsen, Henrik
Haller, Bernhard
Einwächter, Henrik
Weber, Andreas
Abdelhafez, Mohamed
Bajbouj, Monther
Brown, Hayley
Schmid, Roland M.
von Delius, Stefan
author_facet Klare, Peter
Phlipsen, Henrik
Haller, Bernhard
Einwächter, Henrik
Weber, Andreas
Abdelhafez, Mohamed
Bajbouj, Monther
Brown, Hayley
Schmid, Roland M.
von Delius, Stefan
author_sort Klare, Peter
collection PubMed
description BACKGROUND AND STUDY AIMS : Longer observation times are associated with increased adenoma detection rates (ADR) in the entire colon. However, adenomas in the proximal colon are at risk of being missed during colonoscopy. The aim of this study was to investigate the impact of observation time on detection of adenomatous polyps in the proximal colon. PATIENTS AND METHODS : This was a prospective study at a university hospital in Germany. Colonoscopies were conducted using magnetic endoscope imaging (MEI) in order to determine the exact position of the scope. Exact observation times spent for the detection of polyps in the proximal and distal colon segments were assessed. The primary outcome was adenoma detection in the proximal colon. ROC curves were generated in order to test the correlation between observation time and adenoma detection. Logistic regression analysis was used to check for interfering factors. RESULTS:  A total 480 procedures with 538 polyps were available for analysis. The overall adenoma detection rate was 38.5 %. ADR in the proximal colon was 28.0 %. There was a significant association between observation time in the proximal colon and the detection of proximal adenomas ( P  < 0.001). The impact of the time factor on ADR was stronger in the proximal compared to the distal colon ( P  = 0.030). A net period of 4 min 7 sec was found to be the minimum time span for sufficient adenoma detection in the proximal colon. CONCLUSION : Observation time is significant in terms of adenoma detection in the proximal colon. The impact of observation time on ADR is stronger in the proximal compared to the distal colon. In the proximal colon a minimum time span of 4 minutes should be spent in order to ensure adequate adenoma detection.
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spelling pubmed-57189072017-12-07 Longer observation time increases adenoma detection in the proximal colon – a prospective study Klare, Peter Phlipsen, Henrik Haller, Bernhard Einwächter, Henrik Weber, Andreas Abdelhafez, Mohamed Bajbouj, Monther Brown, Hayley Schmid, Roland M. von Delius, Stefan Endosc Int Open BACKGROUND AND STUDY AIMS : Longer observation times are associated with increased adenoma detection rates (ADR) in the entire colon. However, adenomas in the proximal colon are at risk of being missed during colonoscopy. The aim of this study was to investigate the impact of observation time on detection of adenomatous polyps in the proximal colon. PATIENTS AND METHODS : This was a prospective study at a university hospital in Germany. Colonoscopies were conducted using magnetic endoscope imaging (MEI) in order to determine the exact position of the scope. Exact observation times spent for the detection of polyps in the proximal and distal colon segments were assessed. The primary outcome was adenoma detection in the proximal colon. ROC curves were generated in order to test the correlation between observation time and adenoma detection. Logistic regression analysis was used to check for interfering factors. RESULTS:  A total 480 procedures with 538 polyps were available for analysis. The overall adenoma detection rate was 38.5 %. ADR in the proximal colon was 28.0 %. There was a significant association between observation time in the proximal colon and the detection of proximal adenomas ( P  < 0.001). The impact of the time factor on ADR was stronger in the proximal compared to the distal colon ( P  = 0.030). A net period of 4 min 7 sec was found to be the minimum time span for sufficient adenoma detection in the proximal colon. CONCLUSION : Observation time is significant in terms of adenoma detection in the proximal colon. The impact of observation time on ADR is stronger in the proximal compared to the distal colon. In the proximal colon a minimum time span of 4 minutes should be spent in order to ensure adequate adenoma detection. © Georg Thieme Verlag KG 2017-12 2017-12-06 /pmc/articles/PMC5718907/ /pubmed/29218322 http://dx.doi.org/10.1055/s-0043-121072 Text en https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Klare, Peter
Phlipsen, Henrik
Haller, Bernhard
Einwächter, Henrik
Weber, Andreas
Abdelhafez, Mohamed
Bajbouj, Monther
Brown, Hayley
Schmid, Roland M.
von Delius, Stefan
Longer observation time increases adenoma detection in the proximal colon – a prospective study
title Longer observation time increases adenoma detection in the proximal colon – a prospective study
title_full Longer observation time increases adenoma detection in the proximal colon – a prospective study
title_fullStr Longer observation time increases adenoma detection in the proximal colon – a prospective study
title_full_unstemmed Longer observation time increases adenoma detection in the proximal colon – a prospective study
title_short Longer observation time increases adenoma detection in the proximal colon – a prospective study
title_sort longer observation time increases adenoma detection in the proximal colon – a prospective study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5718907/
https://www.ncbi.nlm.nih.gov/pubmed/29218322
http://dx.doi.org/10.1055/s-0043-121072
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