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Complement 5a Receptor deficiency does not influence adverse cardiac remodeling after pressure-overload in mice
Hypertension is one of the most common risk factors for the development heart failure in the general population. Inflammation plays a central role in this adverse remodeling and eventually to the development of heart failure. Circulating levels of Complement factor 5a (C5a) are increased in hyperten...
Autores principales: | de Haan, Judith J., Bosch, Lena, Borgman, Anouska, Bastemeijer, Marissa, Brans, Maike A. D., van de Weg, Sander M., de Kleijn, Dominique P. V., Sluijter, Joost P. G., el Azzouzi, Hamid, de Jager, Saskia C. A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719022/ https://www.ncbi.nlm.nih.gov/pubmed/29213128 http://dx.doi.org/10.1038/s41598-017-16957-3 |
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