GWAS of the electrocardiographic QT interval in Hispanics/Latinos generalizes previously identified loci and identifies population-specific signals

QT interval prolongation is a heritable risk factor for ventricular arrhythmias and can predispose to sudden death. Most genome-wide association studies (GWAS) of QT were performed in European ancestral populations, leaving other groups uncharacterized. Herein we present the first QT GWAS of Hispani...

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Detalles Bibliográficos
Autores principales: Méndez-Giráldez, Raúl, Gogarten, Stephanie M., Below, Jennifer E., Yao, Jie, Seyerle, Amanda A., Highland, Heather M., Kooperberg, Charles, Soliman, Elsayed Z., Rotter, Jerome I., Kerr, Kathleen F., Ryckman, Kelli K., Taylor, Kent D., Petty, Lauren E., Shah, Sanjiv J., Conomos, Matthew P., Sotoodehnia, Nona, Cheng, Susan, Heckbert, Susan R., Sofer, Tamar, Guo, Xiuqing, Whitsel, Eric A., Lin, Henry J., Hanis, Craig L., Laurie, Cathy C., Avery, Christy L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719082/
https://www.ncbi.nlm.nih.gov/pubmed/29213071
http://dx.doi.org/10.1038/s41598-017-17136-0

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