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The IL-1R/TLR signaling pathway is essential for efficient CD8(+) T-cell responses against hepatitis B virus in the hydrodynamic injection mouse model
The outcome of hepatitis B viral (HBV) infection is determined by the complex interactions between replicating HBV and the immune system. While the role of the adaptive immune system in the resolution of HBV infection has been studied extensively, the contribution of innate immune mechanisms remains...
Autores principales: | Ma, Zhiyong, Liu, Jia, Wu, Weimin, Zhang, Ejuan, Zhang, Xiaoyong, Li, Qian, Zelinskyy, Gennadiy, Buer, Jan, Dittmer, Ulf, Kirschning, Carsten J, Lu, Mengji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719144/ https://www.ncbi.nlm.nih.gov/pubmed/28757610 http://dx.doi.org/10.1038/cmi.2017.43 |
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