Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with few effective therapeutic options. Structural remodelling of the extracellular matrix [i.e. collagen cross-linking mediated by the lysyl oxidase (LO) family of enzymes (LOX, LOXL1-4)] might contribute to disease p...

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Detalles Bibliográficos
Autores principales: Tjin, Gavin, White, Eric S., Faiz, Alen, Sicard, Delphine, Tschumperlin, Daniel J., Mahar, Annabelle, Kable, Eleanor P. W., Burgess, Janette K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719253/
https://www.ncbi.nlm.nih.gov/pubmed/29125826
http://dx.doi.org/10.1242/dmm.030114

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719253/
https://www.ncbi.nlm.nih.gov/pubmed/29125826
http://dx.doi.org/10.1242/dmm.030114

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