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Lysyl oxidases regulate fibrillar collagen remodelling in idiopathic pulmonary fibrosis
Idiopathic pulmonary fibrosis (IPF) is a progressive scarring disease of the lung with few effective therapeutic options. Structural remodelling of the extracellular matrix [i.e. collagen cross-linking mediated by the lysyl oxidase (LO) family of enzymes (LOX, LOXL1-4)] might contribute to disease p...
Autores principales: | Tjin, Gavin, White, Eric S., Faiz, Alen, Sicard, Delphine, Tschumperlin, Daniel J., Mahar, Annabelle, Kable, Eleanor P. W., Burgess, Janette K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719253/ https://www.ncbi.nlm.nih.gov/pubmed/29125826 http://dx.doi.org/10.1242/dmm.030114 |
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